U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cdip1 cell death-inducing p53 target 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 360480, updated on 10-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
Cdip1provided by RGD
Official Full Name
cell death-inducing p53 target 1provided by RGD
Primary source
RGD:1310686
See related
EnsemblRapid:ENSRNOG00000003328 AllianceGenome:RGD:1310686
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310686
Summary
Predicted to enable metal ion binding activity. Predicted to act upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and tumor necrosis factor-mediated signaling pathway. Predicted to be located in cytoplasmic side of late endosome membrane; cytoplasmic side of lysosomal membrane; and nucleus. Orthologous to human CDIP1 (cell death inducing p53 target 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 126.8), Brain (RPKM 114.5) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Cdip1 in Genome Data Viewer
Location:
10q12
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (11278213..11303415)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (10773538..10796979)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (10966819..10989937)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 16 open reading frame 96 Neighboring gene uncharacterized LOC134480753 Neighboring gene high mobility group nucleosomal binding domain 4, pseudogene 3 Neighboring gene heme oxygenase 2 Neighboring gene NmrA like redox sensor 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The Charcot Marie Tooth disease protein LITAF is a zinc-binding monotopic membrane protein. Qin W, et al. Biochem J, 2016 Nov 1. PMID 27582497, Free PMC Article
  2. CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent manner. Brown L, et al. EMBO J, 2007 Jul 25. PMID 17599062, Free PMC Article
  3. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, et al. J Proteome Res, 2012 Sep 7. PMID 22871113, Free PMC Article
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC94589

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cytoplasmic side of late endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasmic side of late endosome membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic side of late endosome membrane ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasmic side of late endosome membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in cytoplasmic side of lysosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasmic side of lysosomal membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic side of lysosomal membrane ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasmic side of lysosomal membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
cell death-inducing p53-target protein 1
Names
LITAF-like protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008360.1 → NP_001008361.1  cell death-inducing p53-target protein 1

    See identical proteins and their annotated locations for NP_001008361.1

    Status: PROVISIONAL

    Source sequence(s)
    BC085860
    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A0A8I6A313, A6K4R2
    Related
    ENSRNOP00000084999.1, ENSRNOT00000100719.2
    Conserved Domains (1) summary
    pfam10601
    Location:137 → 205
    zf-LITAF-like; LITAF-like zinc ribbon domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    11278213..11303415
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086264.2 → XP_038942192.1  cell death-inducing p53-target protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A0A8I6A313, A6K4R2
    Conserved Domains (1) summary
    pfam10601
    Location:137 → 205
    zf-LITAF-like; LITAF-like zinc ribbon domain

  2. XM_006245813.5 → XP_006245875.1  cell death-inducing p53-target protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006245875.1

    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A0A8I6A313, A6K4R2
    Conserved Domains (1) summary
    pfam10601
    Location:137 → 205
    zf-LITAF-like; LITAF-like zinc ribbon domain

  3. XM_063269294.1 → XP_063125364.1  cell death-inducing p53-target protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A6K4R2

  4. XM_006245815.5 → XP_006245877.1  cell death-inducing p53-target protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006245877.1

    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A0A8I6A313, A6K4R2
    Conserved Domains (1) summary
    pfam10601
    Location:137 → 205
    zf-LITAF-like; LITAF-like zinc ribbon domain

  5. XM_006245811.5 → XP_006245873.1  cell death-inducing p53-target protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006245873.1

    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A0A8I6A313, A6K4R2
    Conserved Domains (1) summary
    pfam10601
    Location:137 → 205
    zf-LITAF-like; LITAF-like zinc ribbon domain

  6. XM_006245812.5 → XP_006245874.1  cell death-inducing p53-target protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006245874.1

    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A0A8I6A313, A6K4R2
    Conserved Domains (1) summary
    pfam10601
    Location:137 → 205
    zf-LITAF-like; LITAF-like zinc ribbon domain

  7. XM_006245814.5 → XP_006245876.1  cell death-inducing p53-target protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006245876.1

    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A0A8I6A313, A6K4R2
    Related
    ENSRNOP00000004999.3, ENSRNOT00000004999.6
    Conserved Domains (1) summary
    pfam10601
    Location:137 → 205
    zf-LITAF-like; LITAF-like zinc ribbon domain

  8. XM_063269296.1 → XP_063125366.1  cell death-inducing p53-target protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A6K4R2

  9. XM_063269297.1 → XP_063125367.1  cell death-inducing p53-target protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A6K4R2

  10. XM_039086265.2 → XP_038942193.1  cell death-inducing p53-target protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A0A8I6A313, A6K4R2
    Conserved Domains (1) summary
    pfam10601
    Location:137 → 205
    zf-LITAF-like; LITAF-like zinc ribbon domain

  11. XM_063269295.1 → XP_063125365.1  cell death-inducing p53-target protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A6K4R2

  12. XM_006245816.4 → XP_006245878.1  cell death-inducing p53-target protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006245878.1

    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A0A8I6A313, A6K4R2
    Conserved Domains (1) summary
    pfam10601
    Location:137 → 205
    zf-LITAF-like; LITAF-like zinc ribbon domain

  13. XM_063269298.1 → XP_063125368.1  cell death-inducing p53-target protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A6K4R2

  14. XM_039086266.2 → XP_038942194.1  cell death-inducing p53-target protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q5U2U6
    UniProtKB/TrEMBL
    A0A8I6A313, A6K4R2
    Conserved Domains (1) summary
    pfam10601
    Location:137 → 205
    zf-LITAF-like; LITAF-like zinc ribbon domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5U2U6.1 GenPept UniProtKB/Swiss-Prot:Q5U2U6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools