Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search NCBI

Su(var)2-10 - Suppressor of variegation 2-10

Enables STAT family protein binding activity and SUMO ligase activity. Involved in several processes, including piRNA-mediated retrotransposon silencing by heterochromatin formation; positive regulation of somatic stem cell division; and regulation of signal transduction. Located in chromosome, telomeric region; cytoplasm; and nuclear lumen. Is expressed in egg chamber; embryonic brain; larval ventral nerve cord; organism; and ventral nerve cord. Used to study hematologic cancer. Orthologous to several human genes including PIAS2 (protein inhibitor of activated STAT 2) and PIAS3 (protein inhibitor of activated STAT 3). [provided by Alliance of Genome Resources, Oct 2024]

Genes similar to Su(var)2-10

NCBI Orthologs

How was this calculated?

genes for:

Protein alignment

Align

Download data

Download
Species Gene Architecture aa