U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

rgr regular [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35843, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
rgrprovided by FlyBase
Official Full Name
regularprovided by FlyBase
Primary source
FLYBASE:FBgn0267792
Locus tag
Dmel_CG8643
See related
AllianceGenome:FB:FBgn0267792
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG14751; CG8643; Dmel\CG8643; l(2)k02605
Summary
Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in embryonic/larval posterior spiracle; mesoderm; and pole plasm. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See rgr in Genome Data Viewer
Location:
44D4-44D4; 2-59 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8600415..8612295)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4487920..4499800)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Lunapark Neighboring gene uncharacterized protein Neighboring gene Calcium-independent receptor for alpha-latrotoxin Neighboring gene Vacuolar protein sorting 25

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A P element with a novel fusion of reporters identifies regular, a C2H2 zinc-finger gene downstream of the circadian clock. Scully AL, et al. Mol Cell Neurosci, 2002 Apr. PMID 11988018
  2. Notch cooperates with Lozenge/Runx to lock haemocytes into a differentiation programme. Terriente-Felix A, et al. Development, 2013 Feb. PMID 23325760, Free PMC Article
  3. Molecular characterization of teflon, a gene required for meiotic autosome segregation in male Drosophila melanogaster. Arya GH, et al. Genetics, 2006 Sep. PMID 16816414, Free PMC Article
  4. The Drosophila STAM gene homolog is in a tight gene cluster, and its expression correlates to that of the adjacent gene ial. Mesilaty-Gross S, et al. Gene, 1999 Apr 29. PMID 10231582
  5. The negative elongation factor NELF promotes induced transcriptional response of Drosophila ecdysone-dependent genes. Mazina MY, et al. Sci Rep, 2021 Jan 8. PMID 33420323, Free PMC Article

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
regular
Names
CG8643-PA
CG8643-PC
lethal (2) k02605
rgr-PA
rgr-PC

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    8600415..8612295
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001169618.2 → NP_001163089.2  regular, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163089.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JH10
    Conserved Domains (4) summary
    COG5048
    Location:742 → 824
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:719 → 739
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam10545
    Location:335 → 420
    MADF_DNA_bdg; Alcohol dehydrogenase transcription factor Myb/SANT-like
    pfam13465
    Location:763 → 784
    zf-H2C2_2; Zinc-finger double domain

  2. NM_165611.3 → NP_724690.1  regular, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724690.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KG36
    Related
    FBpp0087772
    Conserved Domains (4) summary
    COG5048
    Location:709 → 791
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:686 → 706
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam10545
    Location:302 → 387
    MADF_DNA_bdg; Alcohol dehydrogenase transcription factor Myb/SANT-like
    pfam13465
    Location:730 → 751
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E1JH10 E1JH10
Q5U0W3 Q5U0W3
Q7KG36 Q7KG36

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools