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Hcfc1r1 host cell factor C1 regulator 1 (XPO1-dependent) [ Mus musculus (house mouse) ]

Gene ID: 353502, updated on 2-Nov-2024

Summary

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Official Symbol
Hcfc1r1provided by MGI
Official Full Name
host cell factor C1 regulator 1 (XPO1-dependent)provided by MGI
Primary source
MGI:MGI:2663619
See related
Ensembl:ENSMUSG00000023904 AllianceGenome:MGI:2663619
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
HPIP
Summary
Predicted to be located in nucleoplasm. Is expressed in cranial ganglion; dorsal root ganglion; medulla oblongata lateral wall; olfactory epithelium; and ventral grey horn. Orthologous to human HCFC1R1 (host cell factor C1 regulator 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in stomach adult (RPKM 169.5), adrenal adult (RPKM 159.4) and 25 other tissues See more
Orthologs
human all
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Genomic context

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See Hcfc1r1 in Genome Data Viewer
Location:
17 A3.3; 17 11.98 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (23892570..23894499)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (23673608..23675524)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 25 Neighboring gene ribosomal protein L36 pseudogene Neighboring gene BICD family like cargo adaptor 2 Neighboring gene STARR-positive B cell enhancer ABC_E8656 Neighboring gene THO complex 6 Neighboring gene tumor necrosis factor receptor superfamily, member 12a Neighboring gene claudin 6 Neighboring gene claudin 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Interaction of HCF-1 with a cellular nuclear export factor. Mahajan SS, et al. J Biol Chem, 2002 Nov 15. PMID 12235138, Free PMC Article
  2. Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature. Zhang X, et al. Commun Biol, 2024 Mar 23. PMID 38521877, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
host cell factor C1 regulator 1
Names
HCF-1 beta-propeller-interacting protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001414380.1 → NP_001401309.1  host cell factor C1 regulator 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC154766
    UniProtKB/Swiss-Prot
    Q9CYQ5
    Related
    ENSMUSP00000137336.2, ENSMUST00000180140.8

  2. NM_001414381.1 → NP_001401310.1  host cell factor C1 regulator 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC154766
    UniProtKB/Swiss-Prot
    Q9CYQ5

  3. NM_001414382.1 → NP_001401311.1  host cell factor C1 regulator 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC154766

  4. NM_001414383.1 → NP_001401312.1  host cell factor C1 regulator 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC154766
    UniProtKB/TrEMBL
    J3QPD4
    Related
    ENSMUSP00000137205.2, ENSMUST00000179928.2

  5. NM_001414384.1 → NP_001401313.1  host cell factor C1 regulator 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC154766
    UniProtKB/TrEMBL
    J3QPD4

  6. NM_001414385.1 → NP_001401314.1  host cell factor C1 regulator 1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC154766

  7. NM_001414386.1 → NP_001401315.1  host cell factor C1 regulator 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC154766
    UniProtKB/TrEMBL
    J3QPD4

  8. NM_001414387.1 → NP_001401316.1  host cell factor C1 regulator 1 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC154766

  9. NM_001414470.1 → NP_001401399.1  host cell factor C1 regulator 1 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC154766

  10. NM_181821.3 → NP_861542.1  host cell factor C1 regulator 1 isoform 1

    See identical proteins and their annotated locations for NP_861542.1

    Status: VALIDATED

    Source sequence(s)
    AC154766
    Consensus CDS
    CCDS28455.1
    UniProtKB/Swiss-Prot
    Q9CYQ5
    Related
    ENSMUSP00000024697.5, ENSMUST00000024697.5
    Conserved Domains (1) summary
    pfam15226
    Location:2 → 116
    HPIP; HCF-1 beta-propeller-interacting protein family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    23892570..23894499
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CYQ5.1 GenPept UniProtKB/Swiss-Prot:Q9CYQ5

Gene LinkOut

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