Spata31 spermatogenesis associated 31 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Spata31provided by RGD
Official Full Name: spermatogenesis associated 31provided by RGD
Primary source: RGD:727950
See related: EnsemblRapid:ENSRNOG00000018202 AllianceGenome:RGD:727950
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Aep1; Fam75a4; Spata31a5
Summary: Enables actin binding activity. Predicted to be involved in cell differentiation and spermatogenesis. Located in acrosomal vesicle. Orthologous to several human genes including SPATA31A6 (SPATA31 subfamily A member 6). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Restricted expression toward (RPKM 139.5) See more
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Genomic context

Location:: 17p14

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (249433..255219, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	17	NC_051352.1 (243648..249434, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (2417700..2423486, complement)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

VAD1.3 interacts with beta-actin and syntaxin 1 in vitro.
Title: The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.
VAD1.3 protein/AEP1 is expressed during spermatogenesis and interacts with beta-actin.
Title: Acrosome-specific gene AEP1: identification, characterization and roles in spermatogenesis.

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables actin binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in spermatogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in acrosomal lumen	IEA Inferred from Electronic Annotation more info
located_in acrosomal membrane	IEA Inferred from Electronic Annotation more info
located_in acrosomal vesicle	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: spermatogenesis-associated protein 31

Names: SPATA31 subfamily A member 5; acrosome-expressed protein 1; acrosome-specific protein VAD1.3; family with sequence similarity 75, member A4; spermatogenesis associated 31 subfamily A, member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.