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HCG26 HLA complex group 26 [ Homo sapiens (human) ]

Gene ID: 352961, updated on 10-Oct-2023

Summary

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Official Symbol
HCG26provided by HGNC
Official Full Name
HLA complex group 26provided by HGNC
Primary source
HGNC:HGNC:29671
See related
AllianceGenome:HGNC:29671
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
3.8-1; NCRNA00191; bCX205D4.4; bPG181B23.4
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Genomic context

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Location:
6p21.33
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (31471229..31472408)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (31324354..31325533)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (31439006..31440185)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr6:31430252-31431451 Neighboring gene major histocompatibility complex, class I, X (pseudogene) Neighboring gene HLA complex P5 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:31442899-31443399 Neighboring gene MICB divergent transcript Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:31455304-31456014 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:31456015-31456724 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:31461392-31462273 Neighboring gene MHC class I polypeptide-related sequence B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mapping and characterization of non-HLA multigene assemblages in the human MHC class I region. Venditti CP, et al. Genomics, 1994 Jul 15. PMID 7806210
  2. Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis. Juyal G, et al. Gut, 2015 Apr. PMID 24837172
  3. Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits. Kristiansson K, et al. Circ Cardiovasc Genet, 2012 Apr 1. PMID 22399527, Free PMC Article
  4. Molecular dynamics of MHC genesis unraveled by sequence analysis of the 1,796,938-bp HLA class I region. Shiina T, et al. Proc Natl Acad Sci U S A, 1999 Nov 9. PMID 10557312, Free PMC Article
  5. Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Okada Y, et al. Nat Genet, 2012 Jul 15. PMID 22797727, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.
EBI GWAS Catalog
Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis.
EBI GWAS Catalog
Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
EBI GWAS Catalog
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • HLA complex group 26 (non-protein coding)
  • MHC class I mRNA fragment 3.8-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_002812.3 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL645933

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    31471229..31472408
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NT_113891.3 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    2948554..2949733
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_3

Genomic

  1. NT_167245.2 Reference GRCh38.p14 ALT_REF_LOCI_3

    Range
    2718755..2719934
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_5

Genomic

  1. NT_167247.2 Reference GRCh38.p14 ALT_REF_LOCI_5

    Range
    2813201..2814380
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_6

Genomic

  1. NT_167248.2 Reference GRCh38.p14 ALT_REF_LOCI_6

    Range
    2727116..2728295
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_7

Genomic

  1. NT_167249.2 Reference GRCh38.p14 ALT_REF_LOCI_7

    Range
    2770474..2771653
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    31324354..31325533
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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Chemical Information
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