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Rab9 Rab9 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35221, updated on 2-Nov-2024

Summary

Official Symbol
Rab9provided by FlyBase
Official Full Name
Rab9provided by FlyBase
Primary source
FLYBASE:FBgn0032782
Locus tag
Dmel_CG9994
See related
AllianceGenome:FB:FBgn0032782
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
146494_at; CG9994; Dmel\CG9994; DmRab9; rab9
Summary
Predicted to enable GTPase activity. Involved in retrograde transport, endosome to Golgi. Located in early endosome; late endosome; and trans-Golgi network. Is expressed in several structures, including Bolwig organ; brain; embryonic/larval tracheal section; glial cell; and imaginal disc. Orthologous to human RAB9A (RAB9A, member RAS oncogene family) and RAB9B (RAB9B, member RAS oncogene family). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See Rab9 in Genome Data Viewer
Location:
37E1-37E1; 2-54 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19432574..19435841)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19432574..19435841)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Paxillin Neighboring gene uncharacterized protein Neighboring gene Alkaline phosphatase 12 Neighboring gene RtcB RNA ligase Neighboring gene uncharacterized protein Neighboring gene Ran GTPase activating protein Neighboring gene Heparan sulfate 2-O-sulfotransferase

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein-containing complex binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in Rab protein signal transduction IEA
Inferred from Electronic Annotation
more info
 
involved_in Rab protein signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in retrograde transport, endosome to Golgi IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in early endosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in late endosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in late endosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in phagocytic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in recycling endosome HDA PubMed 
located_in synapse HDA PubMed 
located_in synaptic vesicle HDA PubMed 
located_in trans-Golgi network IDA
Inferred from Direct Assay
more info
PubMed 
located_in vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
Rab9
Names
CG9994-PA
Rab9-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    19432574..19435841
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136122.4NP_609966.1  Rab9 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609966.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VIW6
    Related
    FBpp0080747
    Conserved Domains (2) summary
    cd04116
    Location:8178
    Rab9; Rab GTPase family 9 (Rab9)
    pfam00071
    Location:14177
    Ras; Ras family