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l(2)37Cd lethal (2) 37Cd [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35193, updated on 2-Nov-2024

Summary

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Official Symbol
l(2)37Cdprovided by FlyBase
Official Full Name
lethal (2) 37Cdprovided by FlyBase
Primary source
FLYBASE:FBgn0086445
Locus tag
Dmel_CG10563
See related
AllianceGenome:FB:FBgn0086445
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Cd; CG10563; Dmel\CG10563
Summary
Predicted to contribute to RNA polymerase III type 1 promoter sequence-specific DNA binding activity and RNA polymerase III type 2 promoter sequence-specific DNA binding activity. Predicted to be involved in transcription initiation at RNA polymerase III promoter. Predicted to be part of transcription factor TFIIIC complex. Is expressed in organism. Orthologous to human GTF3C5 (general transcription factor IIIC subunit 5). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See l(2)37Cd in Genome Data Viewer
Location:
37C1-37C1; 2-54 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19127260..19129326)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19127260..19129326)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Prohibitin 1 Neighboring gene lethal (2) 37Cb Neighboring gene Asparaginyl-tRNA synthetase Neighboring gene Dynactin 6, p27 subunit Neighboring gene RNA polymerase I and III subunit D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Developmental control of transduced dopa decarboxylase genes in D. melanogaster. Marsh JL, et al. Mol Gen Genet, 1985. PMID 2989656
  2. BTB protein, dKLHL18/CG3571, serves as an adaptor subunit for a dCul3 ubiquitin ligase complex. Fujiyama-Nakamura S, et al. Genes Cells, 2009 Aug. PMID 19624754
  3. Modulated modularity clustering as an exploratory tool for functional genomic inference. Stone EA, et al. PLoS Genet, 2009 May. PMID 19424432, Free PMC Article
  4. A diphenol oxidase gene is part of a cluster of genes involved in catecholamine metabolism and sclerotization in Drosophila. II. Molecular localization of the Dox-A2 coding region. Pentz ES, et al. Genetics, 1986 Apr. PMID 3007281, Free PMC Article
  5. Molecular mapping of a gene cluster flanking the Drosophila Dopa decarboxylase gene. Gilbert D, et al. Genetics, 1984 Apr. PMID 6425116, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
contributes_to RNA polymerase III type 1 promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to RNA polymerase III type 2 promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in transcription initiation at RNA polymerase III promoter IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of transcription factor TFIIIC complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFIIIC complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
lethal (2) 37Cd
Names
CG10563-PA
l(2)37Cd-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    19127260..19129326
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136103.3 → NP_609947.1  lethal (2) 37Cd [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609947.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5BIF0, Q9VIZ2
    Related
    FBpp0080700
    Conserved Domains (1) summary
    pfam09734
    Location:13 → 303
    Tau95; RNA polymerase III transcription factor (TF)IIIC subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5BIF0 Q5BIF0
Q961P2 Q961P2
Q9VIZ2 Q9VIZ2

Gene LinkOut

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