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Acp36DE Accessory gland protein 36DE [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35096, updated on 18-Sep-2024

Summary

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Official Symbol
Acp36DEprovided by FlyBase
Official Full Name
Accessory gland protein 36DEprovided by FlyBase
Primary source
FLYBASE:FBgn0011559
Locus tag
Dmel_CG7157
See related
AllianceGenome:FB:FBgn0011559
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
A36DE; Acp; Acp36D; Acp36De; AcpDE36; anon-WO0140519.55; CG7157; CT22109; Dmel\CG7157
Summary
Involved in sperm storage. Located in extracellular space. Is expressed in adult head; adult hemolymph; and reproductive system. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See Acp36DE in Genome Data Viewer
Location:
36F3-36F3; 2-53 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18356047..18359028, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18356047..18359026, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45721 Neighboring gene long non-coding RNA:CR44489 Neighboring gene Fasciclin 3 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44486

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cleavage of the Drosophila seminal protein Acp36DE in mated females enhances its sperm storage activity. Avila FW, et al. J Insect Physiol, 2017 Aug. PMID 28676322, Free PMC Article
  2. An early role for the Drosophila melanogaster male seminal protein Acp36DE in female sperm storage. Bloch Qazi MC, et al. J Exp Biol, 2003 Oct. PMID 12939382
  3. Localization of the Drosophila male accessory gland protein Acp36DE in the mated female suggests a role in sperm storage. Bertram MJ, et al. Insect Biochem Mol Biol, 1996 Sep-Oct. PMID 9014340
  4. The role of male accessory gland protein Acp36DE in sperm competition in Drosophila melanogaster. Chapman T, et al. Proc Biol Sci, 2000 Jun 7. PMID 10885514, Free PMC Article
  5. Sperm competition: defining the rules of engagement. Karr TL, et al. Curr Biol, 1999 Oct 21. PMID 10531020

See all (100) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mutations of Acp36DE's cleavage site that slowed or prevented cleavage of the protein slowed the accumulation of sperm into storage, although they did not affect uterine conformational changes in mated females.
    Title: Cleavage of the Drosophila seminal protein Acp36DE in mated females enhances its sperm storage activity.
  2. Mates of males lacking Acp36DE, which is needed for the accumulation of sperm in the storage organs, fail to complete the full sequence of the conformational changes in the mated female's uterus that occur during and immediately after mating.
    Title: Acp36DE is required for uterine conformational changes in mated Drosophila females.
  3. once sperm storage has initiated, Acp36DE acts as a guidance factor helping subsequent sperm move into storage
    Title: An early role for the Drosophila melanogaster male seminal protein Acp36DE in female sperm storage.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables hormone activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in mating plug formation TAS
Traceable Author Statement
more info
 PubMed 
involved_in negative regulation of female receptivity, post-mating NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in sexual reproduction HEP PubMed 
involved_in sexual reproduction IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in sperm competition IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in sperm competition TAS
Traceable Author Statement
more info
 PubMed 
involved_in sperm storage IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sperm storage TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
 PubMed 
located_in extracellular region TAS
Traceable Author Statement
more info
 PubMed 
located_in extracellular space HDA PubMed 
located_in extracellular space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular space ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
accessory gland protein 36DE
Names
36DE accessory gland protein
Acp36DE-PA
Acp36DE-PB
CG7157-PA
CG7157-PB
accessory gland peptide 36DE
accessory gland protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    18356047..18359028 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299111.2 → NP_001286040.1  accessory gland protein 36DE, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286040.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O46198, Q9U9Y5, Q9V3R1
    UniProtKB/TrEMBL
    X2J8Y6
    Conserved Domains (1) summary
    PRK13729
    Location:577 → 682
    PRK13729; conjugal transfer pilus assembly protein TraB; Provisional

  2. NM_078870.4 → NP_523594.1  accessory gland protein 36DE, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523594.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O46198, Q9U9Y5, Q9V3R1
    UniProtKB/TrEMBL
    X2J8Y6
    Related
    FBpp0080607
    Conserved Domains (1) summary
    PRK13729
    Location:577 → 682
    PRK13729; conjugal transfer pilus assembly protein TraB; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9V3R1.1 Q9V3R1
X2J8Y6 X2J8Y6

Gene LinkOut

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