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CG9426 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34719, updated on 28-Oct-2024

Summary

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Official Symbol
CG9426provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032485
Locus tag
Dmel_CG9426
See related
AllianceGenome:FB:FBgn0032485
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG9426; Ipp
Summary
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in larval muscle system; larval somatic muscle cell; and organism. Orthologous to human IPP (intracisternal A particle-promoted polypeptide). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See CG9426 in Genome Data Viewer
Location:
34A10-34A10; 2-47 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13216290..13219923, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13216290..13219923, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene kekkon 4 Neighboring gene small nuclear RNA U2 at 34AB b Neighboring gene mitochondrial translation release factor 1 Neighboring gene Ski6 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila. Arama E, et al. PLoS Biol, 2007 Oct. PMID 17880263, Free PMC Article
  2. Genome-wide studies of the multi-zinc finger Drosophila Suppressor of Hairy-wing protein in the ovary. Soshnev AA, et al. Nucleic Acids Res, 2012 Jul. PMID 22406832, Free PMC Article
  3. Flying through the drosophila cytoskeletal genome. Goldstein LS, et al. J Cell Biol, 2000 Jul 24. PMID 10908588, Free PMC Article
  4. Wg/Wnt1 and Erasp link ER stress to proapoptotic signaling in an autosomal dominant retinitis pigmentosa model. Park JE, et al. Exp Mol Med, 2023 Jul. PMID 37464094, Free PMC Article
  5. A protein network-guided screen for cell cycle regulators in Drosophila. Guest ST, et al. BMC Syst Biol, 2011 May 6. PMID 21548953, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin-like ligase-substrate adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of Cul3-RING ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9426-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    13216290..13219923 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135772.2 → NP_609616.1  uncharacterized protein Dmel_CG9426 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609616.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VK21
    Related
    FBpp0080063
    Conserved Domains (7) summary
    smart00612
    Location:385 → 431
    Kelch; Kelch domain
    PHA03098
    Location:78 → 558
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:468 → 512
    Kelch; KELCH repeat [structural motif]
    pfam00651
    Location:73 → 179
    BTB; BTB/POZ domain
    pfam01344
    Location:515 → 557
    Kelch_1; Kelch motif
    pfam07707
    Location:187 → 289
    BACK; BTB And C-terminal Kelch
    pfam13964
    Location:467 → 516
    Kelch_6; Kelch motif
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VK21 Q9VK21

Gene LinkOut

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