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witty without maturity [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34145, updated on 2-Nov-2024

Summary

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Official Symbol
wittyprovided by FlyBase
Official Full Name
without maturityprovided by FlyBase
Primary source
FLYBASE:FBgn0032023
Locus tag
Dmel_CG14274
See related
AllianceGenome:FB:FBgn0032023
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG14274; Dmel\CG14274
Summary
Predicted to be involved in regulation of cholinergic synaptic transmission and sleep. Is expressed in adult head. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See witty in Genome Data Viewer
Location:
29A5-29B1; 2-31 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8338287..8342056)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8338287..8342056)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene stratum Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45371 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dichotomous cis-regulatory motifs mediate the maturation of the neuromuscular junction by retrograde BMP signaling. Vuilleumier R, et al. Nucleic Acids Res, 2022 Sep 23. PMID 36029115, Free PMC Article
  2. Crooked, coiled and crimpled are three Ly6-like proteins required for proper localization of septate junction components. Nilton A, et al. Development, 2010 Jul. PMID 20570942, Free PMC Article
  3. boudin is required for septate junction organisation in Drosophila and codes for a diffusible protein of the Ly6 superfamily. Hijazi A, et al. Development, 2009 Jul. PMID 19502482
  4. Genetic basis and repeatability for desiccation resistance in Drosophila melanogaster (Diptera: Drosophilidae). Fanara JJ, et al. Genetica, 2024 Feb. PMID 38102503
  5. A single-cell transcriptomic atlas of complete insect nervous systems across multiple life stages. Corrales M, et al. Neural Dev, 2022 Aug 24. PMID 36002881, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in regulation of synaptic transmission, cholinergic IEA
Inferred from Electronic Annotation
more info
  
involved_in sleep IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of synapse maturation IEP
Inferred from Expression Pattern
more info
 PubMed 

General protein information

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Preferred Names
without maturity
Names
CG14274-PA
witty-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    8338287..8342056
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135368.3 → NP_609212.2  without maturity [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609212.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V4N0, Q9VLP0
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VLP0 Q9VLP0

Gene LinkOut

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