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CG4496 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34000, updated on 2-Nov-2024

Summary

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Official Symbol
CG4496provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031894
Locus tag
Dmel_CG4496
See related
AllianceGenome:FB:FBgn0031894
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG4496
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in organism and spermatozoon. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG4496 in Genome Data Viewer
Location:
27E4-27E4; 2-25 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7185461..7190010, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7185461..7190010, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR46210 Neighboring gene long non-coding RNA:CR44613 Neighboring gene Mitochondrial calcium uptake 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Revisiting the protein-coding gene catalog of Drosophila melanogaster using 12 fly genomes. Lin MF, et al. Genome Res, 2007 Dec. PMID 17989253, Free PMC Article
  2. Genetic modifier screens reveal new components that interact with the Drosophila dystroglycan-dystrophin complex. Kucherenko MM, et al. PLoS One, 2008 Jun 11. PMID 18545683, Free PMC Article
  3. Oviposition behaviour in Drosophila melanogaster: Genetic and behavioural decoupling between oviposition acceptance and preference for natural fruits. Fanara JJ, et al. J Evol Biol, 2023 Jan. PMID 36357966
  4. Genomics of Recombination Rate Variation in Temperature-Evolved Drosophila melanogaster Populations. Winbush A, et al. Genome Biol Evol, 2021 Jan 7. PMID 33247719, Free PMC Article
  5. The genetic architecture of odor-guided behavior in Drosophila melanogaster. Anholt RR, et al. Behav Genet, 2001 Jan. PMID 11529271

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables zinc ion binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG4496-PA
CG4496-PB
CG4496-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    7185461..7190010 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135257.1 → NP_609101.1  uncharacterized protein Dmel_CG4496, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609101.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q3ZAM5, Q9VM37
    Related
    FBpp0079047, FBtr0079419
    Conserved Domains (3) summary
    sd00017
    Location:433 → 453
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:245 → 267
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:259 → 282
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001298779.1 → NP_001285708.1  uncharacterized protein Dmel_CG4496, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285708.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q3ZAM5, Q9VM37
    Conserved Domains (3) summary
    sd00017
    Location:433 → 453
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:245 → 267
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:259 → 282
    zf-H2C2_2; Zinc-finger double domain

  3. NM_001298778.1 → NP_001285707.1  uncharacterized protein Dmel_CG4496, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285707.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q3ZAM5, Q9VM37
    Conserved Domains (3) summary
    sd00017
    Location:433 → 453
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:245 → 267
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:259 → 282
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MRU2 Q8MRU2
Q9VM37 Q9VM37

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