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CG9175 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33862, updated on 2-Nov-2024

Summary

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Official Symbol
CG9175provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031779
Locus tag
Dmel_CG9175
See related
AllianceGenome:FB:FBgn0031779
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG9175; Sec12
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and regulation of COPII vesicle coating. Located in endoplasmic reticulum. Is expressed in several structures, including adult head; gland; gut section; hindgut proper primordium; and larval ventral nerve cord. Orthologous to human PREB (prolactin regulatory element binding). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG9175 in Genome Data Viewer
Location:
26B5-26B5; 2-18 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6096698..6098966, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6096698..6098966, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44773 Neighboring gene Kruppel homolog 1 Neighboring gene uncharacterized protein Neighboring gene stathmin Neighboring gene uncharacterized protein Neighboring gene Actin-related protein 2/3 complex, subunit 4 Neighboring gene WD repeat domain 79

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of two pathways mediating protein targeting from ER to lipid droplets. Song J, et al. Nat Cell Biol, 2022 Sep. PMID 36050470, Free PMC Article
  2. The ArfGAP Drongo Promotes Actomyosin Contractility during Collective Cell Migration by Releasing Myosin Phosphatase from the Trailing Edge. Zeledon C, et al. Cell Rep, 2019 Sep 17. PMID 31533044
  3. A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. D'Ambrosio MV, et al. J Cell Biol, 2010 Nov 1. PMID 21041442, Free PMC Article
  4. Systematic analysis of the transcriptional switch inducing migration of border cells. Borghese L, et al. Dev Cell, 2006 Apr. PMID 16580994, Free PMC Article
  5. Genome-wide analyses of Shavenbaby target genes reveals distinct features of enhancer organization. Menoret D, et al. Genome Biol, 2013 Aug 23. PMID 23972280, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of COPII vesicle coating IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in endomembrane system HDA PubMed 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9175-PA
CG9175-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    6096698..6098966 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_164681.3 → NP_723155.1  uncharacterized protein Dmel_CG9175, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723155.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95SQ7, Q9VMH4
    Related
    FBpp0078843
    Conserved Domains (3) summary
    COG2319
    Location:190 → 421
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:190 → 226
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:190 → 420
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. NM_135151.4 → NP_608995.2  uncharacterized protein Dmel_CG9175, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608995.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95SQ7, Q9VMH4
    Related
    FBpp0078842
    Conserved Domains (3) summary
    COG2319
    Location:190 → 421
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:190 → 226
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:190 → 420
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95SQ7 Q95SQ7
Q9VMH4 Q9VMH4

Gene LinkOut

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