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CG11149 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33800, updated on 18-Sep-2024

Summary

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Official Symbol
CG11149provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031732
Locus tag
Dmel_CG11149
See related
AllianceGenome:FB:FBgn0031732
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
dibeta3GnT4; Dmel\CG11149
Summary
Predicted to enable glucuronosyltransferase activity. Predicted to be involved in protein O-linked mannosylation. Predicted to be located in Golgi apparatus. Is expressed in adult head. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A13. Orthologous to human B4GAT1 (beta-1,4-glucuronyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG11149 in Genome Data Viewer
Location:
25F3-25F3; 2-17 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5718121..5720899, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5718121..5720899, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44818 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene septin interacting protein 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phenotype-based clustering of glycosylation-related genes by RNAi-mediated gene silencing. Yamamoto-Hino M, et al. Genes Cells, 2015 Jun. PMID 25940448, Free PMC Article
  2. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
  3. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
  4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
  5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables glucuronosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in protein O-linked mannosylation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11149-PA
CG11149-PB
CG11149-PC
CG11149-PD
CG11149-PE
NP_001162889.1
NP_001162890.1
NP_001260102.1
NP_608952.2
NP_723110.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    5718121..5720899 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001169419.2 → NP_001162890.1  uncharacterized protein Dmel_CG11149, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001162890.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0IGW5, Q8SYJ5
    Conserved Domains (1) summary
    pfam13896
    Location:130 → 467
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  2. NM_135108.3 → NP_608952.2  uncharacterized protein Dmel_CG11149, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608952.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SYJ5, Q9VMN1
    Related
    FBpp0078799
    Conserved Domains (1) summary
    pfam13896
    Location:130 → 485
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  3. NM_001169418.1 → NP_001162889.1  uncharacterized protein Dmel_CG11149, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001162889.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0IGW5, Q8SYJ5
    Conserved Domains (1) summary
    pfam13896
    Location:130 → 467
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  4. NM_164657.1 → NP_723110.1  uncharacterized protein Dmel_CG11149, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723110.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SYJ5, Q9VMN1
    Related
    FBpp0078800, FBtr0079169
    Conserved Domains (1) summary
    pfam13896
    Location:130 → 485
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  5. NM_001273173.1 → NP_001260102.1  uncharacterized protein Dmel_CG11149, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260102.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0IGW5, Q8SYJ5
    Conserved Domains (1) summary
    pfam13896
    Location:130 → 467
    Glyco_transf_49; Glycosyl-transferase for dystroglycan
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0IGW5 Q0IGW5
Q8SYJ5 Q8SYJ5
Q9VMN1 Q9VMN1

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