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sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha [ Danio rerio (zebrafish) ]

Gene ID: 336867, updated on 2-Nov-2024

Summary

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Official Symbol
sgtaprovided by ZNC
Official Full Name
small glutamine rich tetratricopeptide repeat co-chaperone alphaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8811
See related
Ensembl:ENSDARG00000019941 AllianceGenome:ZFIN:ZDB-GENE-030131-8811
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fk20d10; zgc:55741; zgc:77080; wu:fa05b08; wu:fc52b05; wu:fk20d10; si:dkey-6d5.2
Summary
Predicted to enable molecular adaptor activity. Predicted to be involved in post-translational protein targeting to endoplasmic reticulum membrane. Predicted to be part of TRC complex. Predicted to be active in membrane. Orthologous to human SGTA (small glutamine rich tetratricopeptide repeat co-chaperone alpha). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See sgta in Genome Data Viewer
Location:
chromosome: 11
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (14771906..14813053, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (14714247..14755359, complement)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene adenosine receptor A1-like Neighboring gene si:ch73-60h1.1 Neighboring gene uncharacterized LOC137490417 Neighboring gene uncharacterized LOC110440118 Neighboring gene uncharacterized LOC110440095 Neighboring gene uncharacterized LOC137496679

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in post-translational protein targeting to endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of TRC complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
small glutamine-rich tetratricopeptide repeat-containing protein alpha
Names
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212764.1 → NP_997929.1  small glutamine-rich tetratricopeptide repeat-containing protein alpha

    See identical proteins and their annotated locations for NP_997929.1

    Status: PROVISIONAL

    Source sequence(s)
    BC067176
    UniProtKB/TrEMBL
    A0A8M3B6S6, F1QI71, Q6NXA1
    Related
    ENSDARP00000027982.6, ENSDART00000004920.8
    Conserved Domains (3) summary
    sd00006
    Location:91 → 119
    TPR; TPR repeat [structural motif]
    pfam16546
    Location:5 → 63
    SGTA_dimer; Homodimerisation domain of SGTA
    cl26005
    Location:105 → 208
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    14771906..14813053 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021479556.2 → XP_021335231.1  small glutamine-rich tetratricopeptide repeat-containing protein alpha isoform X1

    UniProtKB/TrEMBL
    A0A8M3B6S6, F1QI71, Q6NXA1
    Conserved Domains (3) summary
    sd00006
    Location:91 → 119
    TPR; TPR repeat [structural motif]
    pfam16546
    Location:5 → 63
    SGTA_dimer; Homodimerisation domain of SGTA
    cl26005
    Location:105 → 208
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional

  2. XM_068224117.1 → XP_068080218.1  small glutamine-rich tetratricopeptide repeat-containing protein alpha isoform X1

  3. XM_068224116.1 → XP_068080217.1  small glutamine-rich tetratricopeptide repeat-containing protein alpha isoform X1

  4. XM_068224118.1 → XP_068080219.1  small glutamine-rich tetratricopeptide repeat-containing protein alpha isoform X1

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394807.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    261568..267719 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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