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zfand6 zinc finger, AN1-type domain 6 [ Danio rerio (zebrafish) ]

Gene ID: 336461, updated on 2-Nov-2024

Summary

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Official Symbol
zfand6provided by ZNC
Official Full Name
zinc finger, AN1-type domain 6provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8405
See related
Ensembl:ENSDARG00000098443 AllianceGenome:ZFIN:ZDB-GENE-030131-8405
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
AWP1; fb11b11; wu:fb11b11; zgc:101121
Summary
Predicted to enable polyubiquitin modification-dependent protein binding activity. Predicted to be involved in protein targeting to peroxisome. Orthologous to human ZFAND6 (zinc finger AN1-type containing 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See zfand6 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (10562118..10583144)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (10320011..10341037)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496148 Neighboring gene 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) Neighboring gene uncharacterized LOC137496149 Neighboring gene fumarylacetoacetate hydrolase (fumarylacetoacetase) Neighboring gene uncharacterized LOC137496091 Neighboring gene cortexin domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Assignment of Functional Relevance to Genes at Type 2 Diabetes-Associated Loci Through Investigation of β-Cell Mass Deficits. O'Hare EA, et al. Mol Endocrinol, 2016 Apr. PMID 26963759, Free PMC Article
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein targeting to peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
AN1-type zinc finger protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001328569.1 → NP_001315498.1  AN1-type zinc finger protein 6 isoform 1

    Status: VALIDATED

    Source sequence(s)
    CU695017, EH553618, EH571939
    UniProtKB/TrEMBL
    A0A8N7XJ83, Q6DGC3, Q6PH53
    Related
    ENSDARP00000156825.1, ENSDART00000193520.1
    Conserved Domains (2) summary
    smart00154
    Location:173 → 210
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:10 → 33
    zf-A20; A20-like zinc finger

  2. NM_001328570.1 → NP_001315499.1  AN1-type zinc finger protein 6 isoform 2

    Status: VALIDATED

    Source sequence(s)
    CU695017, EH553618, EH571939
    UniProtKB/TrEMBL
    A0A2R8QU43, A0A8M1PA77
    Related
    ENSDARP00000157049.1, ENSDART00000185188.1

  3. NM_205760.2 → NP_991323.2  AN1-type zinc finger protein 6 isoform 1

    Status: VALIDATED

    Source sequence(s)
    CU695017, EH553618, EH571939
    UniProtKB/TrEMBL
    A0A8N7XJ83, Q6DGC3, Q6PH53
    Related
    ENSDARP00000136708.1, ENSDART00000168801.3
    Conserved Domains (2) summary
    smart00154
    Location:173 → 210
    ZnF_AN1; AN1-like Zinc finger
    pfam01754
    Location:10 → 33
    zf-A20; A20-like zinc finger

RNA

  1. NR_137317.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    CU695017, EH553618, EH571939

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    10562118..10583144
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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