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zwilch zwilch kinetochore protein [ Danio rerio (zebrafish) ]

Gene ID: 336439, updated on 2-Nov-2024

Summary

Official Symbol
zwilchprovided by ZNC
Official Full Name
zwilch kinetochore proteinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050420-101
See related
Ensembl:ENSDARG00000057100 AllianceGenome:ZFIN:ZDB-GENE-050420-101
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fb10f09; si:ch211-242m18.4
Summary
Predicted to be involved in mitotic spindle assembly checkpoint signaling and protein localization to kinetochore. Predicted to act upstream of or within cell division. Predicted to be located in kinetochore. Predicted to be part of RZZ complex. Orthologous to human ZWILCH (zwilch kinetochore protein). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See zwilch in Genome Data Viewer
Location:
chromosome: 18
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (19456639..19472646)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (19467573..19483580)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD18 Neighboring gene small nucleolar RNA SNORD16 Neighboring gene ribosomal protein L4 Neighboring gene lactase-like b Neighboring gene small nuclear RNA activating complex, polypeptide 5 Neighboring gene SMAD family member 6b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in mitotic spindle assembly checkpoint signaling IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitotic spindle assembly checkpoint signaling ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein localization to kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of RZZ complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of RZZ complex IEA
Inferred from Electronic Annotation
more info
 
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
 
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein zwilch homolog
Names
Zwilch, kinetochore associated, homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199735.1NP_001186664.1  protein zwilch homolog

    See identical proteins and their annotated locations for NP_001186664.1

    Status: VALIDATED

    Source sequence(s)
    CT863714, CT954222
    UniProtKB/Swiss-Prot
    A5WWB6, Q1JQ30, Q501W8
    Related
    ENSDARP00000074147.4, ENSDART00000079695.5
    Conserved Domains (1) summary
    pfam09817
    Location:26576
    DUF2352; Uncharacterized conserved protein (DUF2352)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    19456639..19472646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)