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vps37a VPS37A subunit of ESCRT-I [ Danio rerio (zebrafish) ]

Gene ID: 336368, updated on 12-Sep-2024

Summary

Official Symbol
vps37aprovided by ZNC
Official Full Name
VPS37A subunit of ESCRT-Iprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8312
See related
Ensembl:ENSDARG00000017119 AllianceGenome:ZFIN:ZDB-GENE-030131-8312
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb08f03; fj42c03; zgc:73244; zgc:77637; wu:fb08f03; wu:fj42c03
Summary
Acts upstream of or within locomotory behavior. Predicted to be located in late endosome membrane. Predicted to be part of ESCRT I complex. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 53. Orthologous to human VPS37A (VPS37A subunit of ESCRT-I). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See vps37a in Genome Data Viewer
Location:
chromosome: 1
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (16463079..16480213)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (15770142..15787276)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U3 Neighboring gene serine/threonine-protein kinase VRK1-like Neighboring gene uncharacterized LOC110439786 Neighboring gene myotubularin related protein 7b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within locomotory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein targeting to membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein targeting to vacuole IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of ESCRT I complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in late endosome membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
vacuolar protein sorting-associated protein 37A
Names
vacuolar protein sorting 37A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199990.1NP_956284.1  vacuolar protein sorting-associated protein 37A

    See identical proteins and their annotated locations for NP_956284.1

    Status: PROVISIONAL

    Source sequence(s)
    AY398348
    UniProtKB/TrEMBL
    Q6TH08
    Related
    ENSDARP00000073136.4, ENSDART00000078675.6
    Conserved Domains (1) summary
    pfam07200
    Location:225366
    Mod_r; Modifier of rudimentary (Mod(r)) protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    16463079..16480213
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394468.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    107538..125637
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)