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swi2 DNA recombination mediator Swi2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 3361456, updated on 18-Sep-2024

Summary

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Official Symbol
swi2
Official Full Name
DNA recombination mediator Swi2
Primary source
PomBase:SPAC1142.03c
Locus tag
SPOM_SPAC1142.03C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
SPAC17G6.20c
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Genomic context

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See swi2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (3629015..3631458, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein Rqc1 Neighboring gene ncRNA Neighboring gene SGT2 family TPR repeat-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Noc complex Noc2 family subunit Neighboring gene 5S ribosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. New insights into donor directionality of mating-type switching in Schizosaccharomyces pombe. Maki T, et al. PLoS Genet, 2018 May. PMID 29852001, Free PMC Article
  2. The fission yeast homologue of CENP-B, Abp1, regulates directionality of mating-type switching. Aguilar-Arnal L, et al. EMBO J, 2008 Apr 9. PMID 18354497, Free PMC Article
  3. Fission yeast Swi5/Sfr1 and Rhp55/Rhp57 differentially regulate Rhp51-dependent recombination outcomes. Akamatsu Y, et al. EMBO J, 2007 Mar 7. PMID 17304215, Free PMC Article
  4. Fission yeast Swi2 designates cell-type specific donor and stimulates Rad51-driven strand exchange for mating-type switching. Maki T, et al. Nucleic Acids Res, 2023 May 8. PMID 36951094, Free PMC Article
  5. Heterochromatin regulates cell type-specific long-range chromatin interactions essential for directed recombination. Jia S, et al. Cell, 2004 Nov 12. PMID 15537537

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Fission yeast Swi2 designates cell-type specific donor and stimulates Rad51-driven strand exchange for mating-type switching.
    Title: Fission yeast Swi2 designates cell-type specific donor and stimulates Rad51-driven strand exchange for mating-type switching.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables sequence-specific double-stranded DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA recombination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in donor selection IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in gene conversion at mating-type locus IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in gene conversion at mating-type locus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of Swi5-Swi2 complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in mating-type region heterochromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleolus HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
DNA recombination mediator Swi2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3629015..3631458 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019690.3 → NP_001018264.1  DNA recombination mediator Swi2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_001018264.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10668
    UniProtKB/TrEMBL
    H2FH12
Nucleotide Protein
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Gene LinkOut

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