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g3bp1 GTPase activating protein (SH3 domain) binding protein 1 [ Danio rerio (zebrafish) ]

Gene ID: 335512, updated on 2-Nov-2024

Summary

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Official Symbol
g3bp1provided by ZNC
Official Full Name
GTPase activating protein (SH3 domain) binding protein 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-7452
See related
Ensembl:ENSDARG00000017741 AllianceGenome:ZFIN:ZDB-GENE-030131-7452
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fj17h05; zgc:56034; wu:fj17h05
Summary
Enables mRNA 3'-UTR binding activity. Predicted to be involved in stress granule assembly. Predicted to be active in cytoplasmic stress granule and cytosol. Is expressed in neuromast. Orthologous to human G3BP1 (G3BP stress granule assembly factor 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See g3bp1 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (25925666..25935168, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (25627639..25637947, complement)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487589 Neighboring gene glycine receptor, alpha 1 Neighboring gene secreted protein, acidic, cysteine-rich (osteonectin) Neighboring gene solute carrier family 36 member 1 Neighboring gene antioxidant 1 copper chaperone

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA/RNA helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA 3'-UTR binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in stress granule assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasmic stress granule IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ras GTPase-activating protein-binding protein 1
Names
Ras-GTPase-activating protein SH3-domain-binding protein
NP_956250.1
XP_005173159.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199956.1 → NP_956250.1  ras GTPase-activating protein-binding protein 1

    See identical proteins and their annotated locations for NP_956250.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045874
    UniProtKB/TrEMBL
    Q7ZVG3
    Related
    ENSDARP00000121211.1, ENSDART00000139855.3
    Conserved Domains (4) summary
    COG0724
    Location:322 → 423
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd00780
    Location:7 → 135
    NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...
    cd12463
    Location:340 → 419
    RRM_G3BP1; RNA recognition motif found in ras GTPase-activating protein-binding protein 1 (G3BP1) and similar proteins
    pfam15764
    Location:267 → 325
    DUF4693; Domain of unknown function (DUF4693)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    25925666..25935168 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005173102.5 → XP_005173159.1  ras GTPase-activating protein-binding protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BKD5
    Conserved Domains (4) summary
    COG0724
    Location:331 → 431
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd00780
    Location:7 → 135
    NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...
    cd12463
    Location:348 → 427
    RRM_G3BP1; RNA recognition motif found in ras GTPase-activating protein-binding protein 1 (G3BP1) and similar proteins
    cl21589
    Location:217 → 353
    Relaxase; Relaxase/Mobilization nuclease domain
Nucleotide Protein Strain
Heading Accession and Version

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