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l(3)80Fg lethal (3) 80Fg [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3354941, updated on 2-Nov-2024

Summary

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Official Symbol
l(3)80Fgprovided by FlyBase
Official Full Name
lethal (3) 80Fgprovided by FlyBase
Primary source
FLYBASE:FBgn0287183
Locus tag
Dmel_CG40178
See related
AllianceGenome:FB:FBgn0287183
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
80Fg; CG40178; Dmel\CG40178; l(3)Lh4A; l4A
Summary
Is expressed in adult head. Orthologous to human DNAJC16 (DnaJ heat shock protein family (Hsp40) member C16). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See l(3)80Fg in Genome Data Viewer
Location:
80F9-80F9; 3-47 cM
Exon count:
14
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (25798441..26014112, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3LHet NW_001848857.1 (1181140..1396811, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45180 Neighboring gene Fatty acid synthase 3 Neighboring gene antisense RNA:CR45182 Neighboring gene pseudo Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cytogenetic analysis of the third chromosome heterochromatin of Drosophila melanogaster. Koryakov DE, et al. Genetics, 2002 Feb. PMID 11861557, Free PMC Article
  2. Genetic Analysis of the Heterochromatin of Chromosome 3 in Drosophila Melanogaster. II. Vital Loci Identified through Ems Mutagenesis. Marchant GE, et al. Genetics, 1988 Oct. PMID 17246481, Free PMC Article
  3. Identification of regions interacting with ovoD mutations: potential new genes involved in germline sex determination or differentiation in Drosophila melanogaster. Pauli D, et al. Genetics, 1995 Feb. PMID 7713427, Free PMC Article
  4. Essential genes in proximal 3L heterochromatin of Drosophila melanogaster. Schulze S, et al. Mol Gen Genet, 2001 Feb. PMID 11254125
  5. Cell-type specific features of circular RNA expression. Salzman J, et al. PLoS Genet, 2013. PMID 24039610, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

mobile_element

  • Loc: c25805820-25804337 mobile_element_type = transposon:1360{}6377

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
lethal (3) 80Fg
Names
CG40178-PA
CG40178-PB
CG40178-PC
l(3)80Fg-PA
l(3)80Fg-PB
l(3)80Fg-PC
lethal 4A
lethal4A

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    25798441..26014112 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001015187.3 → NP_001015187.2  lethal (3) 80Fg, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001015187.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5BII3, Q6AWH1, Q7PLG1
    Conserved Domains (3) summary
    COG0484
    Location:30 → 94
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    cd02963
    Location:134 → 244
    TRX_DnaJ; TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40) ...
    pfam00226
    Location:30 → 91
    DnaJ; DnaJ domain

  2. NM_001015188.4 → NP_001015188.2  lethal (3) 80Fg, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001015188.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5BII3, Q6AWH1, Q7PLG1
    Conserved Domains (3) summary
    COG0484
    Location:30 → 94
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    cd02963
    Location:134 → 244
    TRX_DnaJ; TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40) ...
    pfam00226
    Location:30 → 91
    DnaJ; DnaJ domain

  3. NM_001276235.1 → NP_001263164.1  lethal (3) 80Fg, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001263164.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5BII3, Q6AWH1, Q7PLG1
    Conserved Domains (3) summary
    COG0484
    Location:30 → 94
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    cd02963
    Location:134 → 244
    TRX_DnaJ; TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40) ...
    pfam00226
    Location:30 → 91
    DnaJ; DnaJ domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7PLG1 Q7PLG1

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