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arrdc2 arrestin domain containing 2 [ Danio rerio (zebrafish) ]

Gene ID: 335206, updated on 12-Sep-2024

Summary

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Official Symbol
arrdc2provided by ZNC
Official Full Name
arrestin domain containing 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-7146
See related
Ensembl:ENSDARG00000020761 AllianceGenome:ZFIN:ZDB-GENE-030131-7146
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:85652; wu:fb70a10; wu:fk89c02
Summary
Predicted to be involved in protein transport. Predicted to be active in cytoplasm and plasma membrane. Is expressed in basal plate midbrain region; blood vessel; nervous system; neural rod; and pronephric duct. Orthologous to human ARRDC2 (arrestin domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See arrdc2 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (13524503..13533782)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (13466845..13476123)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene homer scaffold protein 3b Neighboring gene uncharacterized LOC137496676 Neighboring gene si:dkey-13m1.5 Neighboring gene si:ch211-1a19.2 Neighboring gene secreted immunoglobulin domain 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. On the origins of arrestin and rhodopsin. Alvarez CE. BMC Evol Biol, 2008 Jul 29. PMID 18664266, Free PMC Article
  2. Expression of Protein-Coding Gene Orthologs in Zebrafish and Mouse Inner Ear Non-sensory Supporting Cells. Giffen KP, et al. Front Neurosci, 2019. PMID 31680844, Free PMC Article
  3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
  
involved_in protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
arrestin domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199939.1 → NP_956233.1  arrestin domain-containing protein 2

    See identical proteins and their annotated locations for NP_956233.1

    Status: PROVISIONAL

    Source sequence(s)
    AY423023
    UniProtKB/TrEMBL
    Q6TEM6
    Related
    ENSDARP00000017762.8, ENSDART00000011362.9
    Conserved Domains (2) summary
    smart01017
    Location:183 → 308
    Arrestin_C; Arrestin (or S-antigen), C-terminal domain
    pfam00339
    Location:9 → 159
    Arrestin_N; Arrestin (or S-antigen), N-terminal domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    13524503..13533782
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005155942.4 → XP_005155999.1  arrestin domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B1Y2, E9QI61
    Related
    ENSDARP00000113815.1, ENSDART00000139889.3
    Conserved Domains (2) summary
    smart01017
    Location:178 → 303
    Arrestin_C; Arrestin (or S-antigen), C-terminal domain
    pfam00339
    Location:9 → 154
    Arrestin_N; Arrestin (or S-antigen), N-terminal domain
Nucleotide Protein
Heading Accession and Version

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