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lectin-37Da lectin-37Da [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3346222, updated on 18-Sep-2024

Summary

Official Symbol
lectin-37Daprovided by FlyBase
Official Full Name
lectin-37Daprovided by FlyBase
Primary source
FLYBASE:FBgn0053532
Locus tag
Dmel_CG33532
See related
AllianceGenome:FB:FBgn0053532
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AC 007082B; AC007082b; CG33532; CG9978; DL2; Dmel\CG33532
Summary
Enables galactose binding activity. Involved in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; encapsulation of foreign target; and melanization defense response. Located in extracellular region. Is expressed in several structures, including Malpighian tubule; cuticle; embryonic/larval fat body; midgut; and somatic muscle cell. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See lectin-37Da in Genome Data Viewer
Location:
37D6-37D6; 2-54 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19418317..19419029)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19418317..19419029)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene small non-coding RNA 359 Neighboring gene Paxillin Neighboring gene Galactose-specific C-type lectin Neighboring gene lectin-37Db Neighboring gene uncharacterized protein Neighboring gene Alkaline phosphatase 12

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables carbohydrate binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables galactose binding IDA
Inferred from Direct Assay
more info
PubMed 
enables galactose binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables pattern recognition receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular region IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular region ISM
Inferred from Sequence Model
more info
PubMed 

General protein information

Preferred Names
lectin-37Da
Names
CG33532-PA
CG33532-PB
Lectin-37 Da
drosophila lectin 2
lectin
lectin-37Da-PA
lectin-37Da-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    19418317..19419029
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001014489.2NP_001014489.1  lectin-37Da, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014489.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q4V3L4, Q59DY6, Q65Y01
    UniProtKB/TrEMBL
    Q4V3S4
    Conserved Domains (1) summary
    cd00037
    Location:49173
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
  2. NM_001201917.1NP_001188846.1  lectin-37Da, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188846.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q4V3L4, Q59DY6, Q65Y01
    UniProtKB/TrEMBL
    Q4V3S4
    Conserved Domains (1) summary
    cd00037
    Location:49173
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain