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U3-55K U3 small nuclear riboprotein factor 55K [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3346176, updated on 2-Nov-2024

Summary

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Official Symbol
U3-55Kprovided by FlyBase
Official Full Name
U3 small nuclear riboprotein factor 55Kprovided by FlyBase
Primary source
FLYBASE:FBgn0053505
Locus tag
Dmel_CG33505
See related
AllianceGenome:FB:FBgn0053505
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10220; CG33505; Dmel\CG33505
Summary
Enables U3 snoRNA binding activity. Predicted to be located in nucleolus. Predicted to be part of box C/D methylation guide snoRNP complex and small-subunit processome. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; embryonic/larval midgut primordium; mesoderm; and visceral mesoderm derivative. Orthologous to human RRP9 (ribosomal RNA processing 9, U3 small nucleolar RNA binding protein). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See U3-55K in Genome Data Viewer
Location:
51C5-51C5; 2-72 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14858845..14860758, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10746350..10748263, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ercc1 Neighboring gene Ciao1 Neighboring gene Hermansky-Pudlak Syndrome 1 Neighboring gene uncharacterized protein Neighboring gene Pcf11 cleavage and polyadenylation factor subunit Neighboring gene Cytochrome P450 6a22

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A conserved WD40 protein binds the Cajal body localization signal of scaRNP particles. Tycowski KT, et al. Mol Cell, 2009 Apr 10. PMID 19285445, Free PMC Article
  2. The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins. Edlich-Muth C, et al. J Mol Biol, 2015 May 22. PMID 25813344, Free PMC Article
  3. Comparative interactome analysis of α-arrestin families in human and Drosophila. Lee KT, et al. Elife, 2024 Jan 25. PMID 38270169, Free PMC Article
  4. Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster. Juneja P, et al. BMC Genomics, 2016 Nov 28. PMID 27894253, Free PMC Article
  5. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables U3 snoRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables U3 snoRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables snoRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of box C/D methylation guide snoRNP complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleolus ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
U3 small nuclear riboprotein factor 55K
Names
CG33505-PA
U3-55K-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    14858845..14860758 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001014529.3 → NP_001014529.1  U3 small nuclear riboprotein factor 55K [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014529.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MSW9
    Conserved Domains (4) summary
    COG2319
    Location:150 → 484
    WD40; WD40 repeat [General function prediction only]
    pfam04050
    Location:55 → 125
    Upf2; Up-frameshift suppressor 2
    sd00039
    Location:163 → 203
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:156 → 416
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MSW9 Q8MSW9

Gene LinkOut

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