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CG11454 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33175, updated on 18-Sep-2024

Summary

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Official Symbol
CG11454provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031224
Locus tag
Dmel_CG11454
See related
AllianceGenome:FB:FBgn0031224
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cg11454; Dmel\CG11454; dRbm7
Summary
Predicted to enable mRNA binding activity and single-stranded RNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be active in nucleus. Orthologous to several human genes including RBM7 (RNA binding motif protein 7). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG11454 in Genome Data Viewer
Location:
21B3-21B3; 2-0.5 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (143323..144227)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (143323..144227)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase (ubiquinone) 15 kDa subunit Neighboring gene uncharacterized protein Neighboring gene oven mitt Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Pseudouridine synthase 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A conserved virus-induced cytoplasmic TRAMP-like complex recruits the exosome to target viral RNA for degradation. Molleston JM, et al. Genes Dev, 2016 Jul 15. PMID 27474443, Free PMC Article
  2. The drosophila melanogaster genome: translation factors and RNA binding proteins. Lasko P. J Cell Biol, 2000 Jul 24. PMID 10908586, Free PMC Article
  3. Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology. Broderick NA, et al. mBio, 2014 May 27. PMID 24865556, Free PMC Article
  4. Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Phanse S, et al. Data Brief, 2016 Mar. PMID 26870755, Free PMC Article
  5. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables single-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11454-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    143323..144227
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134653.4 → NP_608497.1  uncharacterized protein Dmel_CG11454 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608497.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5BIE3, Q9VPK4
    Related
    FBpp0077775
    Conserved Domains (2) summary
    COG0724
    Location:70 → 210
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12336
    Location:69 → 143
    RRM_RBM7_like; RNA recognition motif in RNA-binding protein 7 (RBM7) and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5BIE3 Q5BIE3
Q95RA2 Q95RA2
Q9VPK4 Q9VPK4

Gene LinkOut

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