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fd19B forkhead domain 19B [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33010, updated on 2-Nov-2024

Summary

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Official Symbol
fd19Bprovided by FlyBase
Official Full Name
forkhead domain 19Bprovided by FlyBase
Primary source
FLYBASE:FBgn0031086
Locus tag
Dmel_CG9571
See related
AllianceGenome:FB:FBgn0031086
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9571; Dmcg9571; Dmel\CG9571; FoxG
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Is expressed in several structures, including anlage in statu nascendi; anterior endoderm anlage; central brain anlage in statu nascendi; foregut anlage in statu nascendi; and head mesoderm anlage. Orthologous to human FOXI3 (forkhead box I3); FOXJ2 (forkhead box J2); and FOXS1 (forkhead box S1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See fd19B in Genome Data Viewer
Location:
19B1-19B1; 1-64 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20091428..20092408, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (19985461..19986441, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Dopamine 2-like receptor Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45628 Neighboring gene uncharacterized protein Neighboring gene Odorant receptor 19b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Association of orthodenticle with natural variation for early embryonic patterning in Drosophila melanogaster. Goering LM, et al. J Exp Zool B Mol Dev Evol, 2009 Dec 15. PMID 19488993, Free PMC Article
  2. The role of binding site cluster strength in Bicoid-dependent patterning in Drosophila. Ochoa-Espinosa A, et al. Proc Natl Acad Sci U S A, 2005 Apr 5. PMID 15793007, Free PMC Article
  3. Evolutionary origins of transcription factor binding site clusters. He X, et al. Mol Biol Evol, 2012 Mar. PMID 22075113, Free PMC Article
  4. Phylogenetic relationships of the Fox (Forkhead) gene family in the Bilateria. Mazet F, et al. Gene, 2003 Oct 16. PMID 14563554
  5. Survey of forkhead domain encoding genes in the Drosophila genome: Classification and embryonic expression patterns. Lee HH, et al. Dev Dyn, 2004 Feb. PMID 14745961

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in anatomical structure morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
forkhead domain 19B
Names
CG9571-PA
fd19B-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    20091428..20092408 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134525.2 → NP_608369.1  forkhead domain 19B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608369.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0IGQ1, Q9W5X5
    Related
    FBpp0070031
    Conserved Domains (1) summary
    cd00059
    Location:58 → 135
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W5X5 Q9W5X5

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