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Vav - Vav guanine nucleotide exchange factor

Enables guanyl-nucleotide exchange factor activity. Involved in several processes, including cell surface receptor protein tyrosine kinase signaling pathway; nervous system development; and regulation of signal transduction. Located in cytosol. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; ganglia; gut section; and mesoderm. Orthologous to human VAV1 (vav guanine nucleotide exchange factor 1); VAV2 (vav guanine nucleotide exchange factor 2); and VAV3 (vav guanine nucleotide exchange factor 3). [provided by Alliance of Genome Resources, Oct 2024]

NCBI Orthologs

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Species Gene Architecture aa