OdsH Ods-site homeobox [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: OdsHprovided by FlyBase
Official Full Name: Ods-site homeoboxprovided by FlyBase
Primary source: FLYBASE:FBgn0026058
Locus tag: Dmel_CG6352
See related: AllianceGenome:FB:FBgn0026058
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG6352; Dmel\CG6352; odsh; odsH; Odsh; OdsH[mel]
Summary: Predicted to enable sequence-specific double-stranded DNA binding activity. Involved in sexual reproduction. Located in extracellular space. Is expressed in embryonic hypopharynx; embryonic ventral epidermis; hypopharynx proper primordium; larval labral sensory complex; and ventral sensory complex primordium. Orthologous to human UNCX (UNC homeobox). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (17791010..17814011)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (17685043..17708044)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Selection with two alleles of X-linkage and its application to the fitness component analysis of OdsH in Drosophila.
Title: Selection with two alleles of X-linkage and its application to the fitness component analysis of OdsH in Drosophila.
A comprehensive evolutionary scenario for the origin and neofunctionalization of the Drosophila speciation gene Odysseus (OdsH).
Title: A comprehensive evolutionary scenario for the origin and neofunctionalization of the Drosophila speciation gene Odysseus (OdsH).
early developing germ cells, including spermatogonia and spermatocytes, are reduced in the OdsH mutant males.
Title: Reduction of germ cells in the Odysseus null mutant causes male fertility defect in Drosophila melanogaster.
normal function of OdsH identified as a modest enhancement of sperm production in young males
Title: The normal function of a speciation gene, Odysseus, and its hybrid sterility effect.
a hybrid-male sterility gene, Odysseus (OdsH), arose by gene duplication in the Drosophila genome
Title: Gene duplication and speciation in Drosophila: evidence from the Odysseus locus.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info
enables sequence-specific double-stranded DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of gene expression	IBA Inferred from Biological aspect of Ancestor more info
involved_in sexual reproduction	HEP more info	PubMed