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castor2 cytosolic arginine sensor for mTORC1 subunit 2 [ Danio rerio (zebrafish) ]

Gene ID: 327294, updated on 17-Aug-2024

Summary

Official Symbol
castor2provided by ZNC
Official Full Name
cytosolic arginine sensor for mTORC1 subunit 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5505
See related
Ensembl:ENSDARG00000018985 AllianceGenome:ZFIN:ZDB-GENE-030131-5505
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
gats; gatsl2; sb:cb509; zgc:55700; zgc:66173; wu:fc27d10; wu:fd20f09; wu:fe01c02
Summary
Predicted to be involved in cellular response to L-arginine and negative regulation of TORC1 signaling. Predicted to be active in cytosol. Is expressed in artery; blood; notochord; and yolk syncytial layer. Orthologous to several human genes including CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 5
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (61361815..61403813)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (60677094..60719092)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene si:ch211-209a2.2 Neighboring gene si:ch211-209a2.1 Neighboring gene RCC1 like Neighboring gene neutrophil cytosolic factor 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in cellular response to L-arginine IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in negative regulation of TORC1 signaling IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
cytosolic arginine sensor for mTORC1 subunit 2
Names
GATS protein-like 2
opposite strand transcription unit to Stag3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199780.2NP_956074.2  cytosolic arginine sensor for mTORC1 subunit 2

    See identical proteins and their annotated locations for NP_956074.2

    Status: PROVISIONAL

    Source sequence(s)
    BC045430
    UniProtKB/TrEMBL
    A0A8M1PDF2, Q7ZVS6
    Related
    ENSDARP00000005214.8, ENSDART00000009507.9
    Conserved Domains (1) summary
    pfam13840
    Location:262322
    ACT_7; ACT domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    61361815..61403813
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)