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cbx2 - chromobox homolog 2 (Drosophila Pc class)

Predicted to enable methylated histone binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in heterochromatin. Predicted to be part of PRC1 complex. Is expressed in several structures, including digestive system; heart; nervous system; pectoral fin bud; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in 46,XY sex reversal 5. Orthologous to human CBX2 (chromobox 2). [provided by Alliance of Genome Resources, Oct 2024]

NCBI Orthologs

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Species Gene Architecture aa