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CG8611 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32725, updated on 18-Sep-2024

Summary

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Official Symbol
CG8611provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0027602
Locus tag
Dmel_CG8611
See related
AllianceGenome:FB:FBgn0027602
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GH02833; cg8611; Dmel\CG8611; DmRH11
Summary
Predicted to enable RNA helicase activity. Predicted to be involved in ribosome biogenesis. Predicted to be active in nucleus. Is expressed in several structures, including embryonic/larval midgut; embryonic/larval muscle cell; extended germ band embryo; spermatozoon; and visceral muscle primordium. Orthologous to human DDX31 (DEAD-box helicase 31). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG8611 in Genome Data Viewer
Location:
16A5-16A5; 1-57 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (17413267..17422145, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17307300..17316178, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43491 Neighboring gene BarH1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Endo-beta-N-acetylglucosaminidase Neighboring gene presidents-cup

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rare recombination events generate sequence diversity among balancer chromosomes in Drosophila melanogaster. Miller DE, et al. Proc Natl Acad Sci U S A, 2016 Mar 8. PMID 26903656, Free PMC Article
  2. DDX56 Binds to Chikungunya Virus RNA To Control Infection. Taschuk F, et al. mBio, 2020 Oct 27. PMID 33109765, Free PMC Article
  3. Stem-loop recognition by DDX17 facilitates miRNA processing and antiviral defense. Moy RH, et al. Cell, 2014 Aug 14. PMID 25126784, Free PMC Article
  4. Evolution of intron/exon structure of DEAD helicase family genes in Arabidopsis, Caenorhabditis, and Drosophila. Boudet N, et al. Genome Res, 2001 Dec. PMID 11731501, Free PMC Article
  5. RNA silencing in the antiviral innate immune defence--role of DEAD-box RNA helicases. Ulvila J, et al. Scand J Immunol, 2010 Mar. PMID 20415780

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA helicase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ribosome biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8611-PA
CG8611-PB
CG8611-PC
NP_001285372.1
NP_573214.1
NP_788922.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    17413267..17422145 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_176749.2 → NP_788922.1  uncharacterized protein Dmel_CG8611, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788922.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q86B47, Q9VX53, Q9Y159
    UniProtKB/TrEMBL
    E8NHB2
    Related
    FBpp0074214
    Conserved Domains (5) summary
    smart00487
    Location:348 → 554
    DEXDc; DEAD-like helicases superfamily
    cd00079
    Location:601 → 757
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam10310
    Location:203 → 285
    DUF2413; Protein of unknown function (DUF2413)
    pfam13959
    Location:805 → 866
    DUF4217; Domain of unknown function (DUF4217)
    cl21455
    Location:332 → 548
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. NM_132986.5 → NP_573214.1  uncharacterized protein Dmel_CG8611, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573214.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NHB2
    Related
    FBpp0074213
    Conserved Domains (5) summary
    smart00487
    Location:347 → 553
    DEXDc; DEAD-like helicases superfamily
    cd00079
    Location:600 → 756
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam10310
    Location:202 → 284
    DUF2413; Protein of unknown function (DUF2413)
    pfam13959
    Location:804 → 865
    DUF4217; Domain of unknown function (DUF4217)
    cl21455
    Location:331 → 547
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. NM_001298443.1 → NP_001285372.1  uncharacterized protein Dmel_CG8611, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285372.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NHB2, X2JKW3
    Conserved Domains (4) summary
    smart00487
    Location:348 → 554
    DEXDc; DEAD-like helicases superfamily
    cd00079
    Location:601 → 757
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam10310
    Location:203 → 285
    DUF2413; Protein of unknown function (DUF2413)
    cl21455
    Location:332 → 548
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q86B47.1 Q86B47
X2JKW3 X2JKW3

Gene LinkOut

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