arf2b ADP-ribosylation factor 2b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: arf2bprovided by ZNC
Official Full Name: ADP-ribosylation factor 2bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5234
See related: Ensembl:ENSDARG00000016393 AllianceGenome:ZFIN:ZDB-GENE-030131-5234
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: arf1l; fa19d09; wu:fa19d09; wu:fb19d05
Summary: Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in MAPK cascade and canonical NF-kappaB signal transduction. Predicted to act upstream of or within protein transport. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human MAP3K14 (mitogen-activated protein kinase kinase kinase 14). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 24

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (36392514..36399271)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (36504442..36511199)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

aa605780 (e-PCR)
- UniSTS:186897

fb19d05.x1 (e-PCR)
- UniSTS:190257

fb19d05.x1 (e-PCR)
- UniSTS:190258

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in MAPK cascade	IBA Inferred from Biological aspect of Ancestor more info
involved_in canonical NF-kappaB signal transduction	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vesicle-mediated transport	IEA Inferred from Electronic Annotation more info
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ADP-ribosylation factor 2b

Names: ADP-ribosylation factor 1 like; arf12b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.