cbx1a chromobox homolog 1a (HP1 beta homolog Drosophila) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cbx1aprovided by ZNC
Official Full Name: chromobox homolog 1a (HP1 beta homolog Drosophila)provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-4945
See related: Ensembl:ENSDARG00000004189 AllianceGenome:ZFIN:ZDB-GENE-030131-4945
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cbx1; zgc:55739; wu:fe14b09
Summary: Predicted to enable chromatin binding activity and methylated histone binding activity. Predicted to be involved in chromatin organization and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in pericentric heterochromatin. Is expressed in brain and retina. Orthologous to human CBX1 (chromobox 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (24060465..24071582)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (23929917..23941034)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb55f02.x1 (e-PCR)
- UniSTS:190739

fe14b09.x1 (e-PCR)
- UniSTS:196182

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info
enables methylated histone binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in heterochromatin formation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in pericentric heterochromatin	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: chromobox protein homolog 1a

Names: chromobox homolog 1 (HP1 beta homolog Drosophila )

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199746.2 → NP_956040.2 chromobox protein homolog 1a

Status: VALIDATED

Source sequence(s)

CR450718, EH457628, EH545424

UniProtKB/TrEMBL

A0A8M1PFU2, F1QM86

Related

ENSDARP00000118656.1, ENSDART00000143088.2

Conserved Domains (2) summary

pfam00385
Location:56 → 96

Chromo; Chromo (CHRromatin Organization MOdifier) domain

pfam01393
Location:145 → 196

Chromo_shadow; Chromo shadow domain