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CG33116 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 326259, updated on 18-Sep-2024

Summary

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Official Symbol
CG33116provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0053116
Locus tag
Dmel_CG33116
See related
AllianceGenome:FB:FBgn0053116
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10355; dCCS1; Dmel\CG33116
Summary
Predicted to enable ethanolaminephosphotransferase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Located in endoplasmic reticulum. Is expressed in several structures, including adult head; embryonic brain; extended germ band embryo; and larval ventral nerve cord. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia. Orthologous to human SELENOI (selenoprotein I). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See CG33116 in Genome Data Viewer
Location:
37F1-37F1; 2-54 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19533479..19537363)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19533479..19537363)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Dolichyl-phosphate mannosyltransferase subunit 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45455 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ceramide phosphoethanolamine biosynthesis in Drosophila is mediated by a unique ethanolamine phosphotransferase in the Golgi lumen. Vacaru AM, et al. J Biol Chem, 2013 Apr 19. PMID 23449981, Free PMC Article
  2. Rapid Low-Cost Assembly of the Drosophila melanogaster Reference Genome Using Low-Coverage, Long-Read Sequencing. Solares EA, et al. G3 (Bethesda), 2018 Oct 3. PMID 30018084, Free PMC Article
  3. Deficiency screening for genomic regions with effects on environmental sensitivity of the sensory bristles of Drosophila melanogaster. Takahashi KH, et al. Evolution, 2012 Sep. PMID 22946809
  4. Innate immune signaling in Drosophila shifts anabolic lipid metabolism from triglyceride storage to phospholipid synthesis to support immune function. Martínez BA, et al. PLoS Genet, 2020 Nov. PMID 33227003, Free PMC Article
  5. Genome-wide transcription profile of field- and laboratory-selected dichlorodiphenyltrichloroethane (DDT)-resistant Drosophila. Pedra JH, et al. Proc Natl Acad Sci U S A, 2004 May 4. PMID 15118106, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ethanolaminephosphotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphotransferase activity, for other substituted phosphate groups IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in phosphatidylethanolamine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG33116-PA
NP_788074.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    19533479..19537363
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_176060.2 → NP_788074.1  uncharacterized protein Dmel_CG33116 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788074.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9G2, Q9VIU4
    Related
    FBpp0080790
    Conserved Domains (1) summary
    cl00453
    Location:13 → 348
    CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8T9G2 Q8T9G2
Q9VIU4 Q9VIU4

Gene LinkOut

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