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Sk2 - Sphingosine kinase 2

Enables D-erythro-sphingosine kinase activity. Involved in several processes, including flight behavior; oviposition; and sphingolipid metabolic process. Located in lysosomal membrane. Is expressed in adult head; anterior midgut primordium; mesoderm; organism; and posterior midgut primordium. Used to study cardiomyopathy and obesity. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to several human genes including SPHK2 (sphingosine kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Genes similar to Sk2

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Species Gene Architecture aa