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CG32344 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 326208, updated on 18-Sep-2024

Summary

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Official Symbol
CG32344provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0052344
Locus tag
Dmel_CG32344
See related
AllianceGenome:FB:FBgn0052344
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cg6994; CG6994; Dmel\CG32344; DmRH20
Summary
Predicted to enable RNA helicase activity. Predicted to be involved in rRNA processing. Predicted to be active in nucleolus. Is expressed in several structures, including embryonic/larval muscle system; extended germ band embryo; gut section; and visceral muscle primordium. Orthologous to human DDX54 (DEAD-box helicase 54). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG32344 in Genome Data Viewer
Location:
61C1-61C1; 3-0.5 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (321233..324720, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (321233..324720, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Rho guanine nucleotide exchange factor 3 Neighboring gene four wheel drive Neighboring gene deadbeat Neighboring gene Ada2a-containing complex component 3 Neighboring gene Protein tyrosine phosphatase Meg Neighboring gene methuselah-like 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. DDX56 Binds to Chikungunya Virus RNA To Control Infection. Taschuk F, et al. mBio, 2020 Oct 27. PMID 33109765, Free PMC Article
  2. Proteomic mapping in live Drosophila tissues using an engineered ascorbate peroxidase. Chen CL, et al. Proc Natl Acad Sci U S A, 2015 Sep 29. PMID 26362788, Free PMC Article
  3. Stem-loop recognition by DDX17 facilitates miRNA processing and antiviral defense. Moy RH, et al. Cell, 2014 Aug 14. PMID 25126784, Free PMC Article
  4. In vivo functional characterization of the SARS-Coronavirus 3a protein in Drosophila. Wong SL, et al. Biochem Biophys Res Commun, 2005 Nov 18. PMID 16212942, Free PMC Article
  5. Evolution of intron/exon structure of DEAD helicase family genes in Arabidopsis, Caenorhabditis, and Drosophila. Boudet N, et al. Genome Res, 2001 Dec. PMID 11731501, Free PMC Article

See all (44) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA helicase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables helicase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG32344-PA
NP_612028.4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    321233..324720 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138184.5 → NP_612028.4  uncharacterized protein Dmel_CG32344 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_612028.4

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SY39
    Related
    FBpp0072475
    Conserved Domains (4) summary
    smart00487
    Location:54 → 243
    DEXDc; DEAD-like helicases superfamily
    cd00079
    Location:263 → 384
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cd00268
    Location:41 → 243
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    pfam08147
    Location:666 → 721
    DBP10CT; DBP10CT (NUC160) domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SY39 Q8SY39

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