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Rrp47 Ribosomal RNA processing 47 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32558, updated on 2-Nov-2024

Summary

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Official Symbol
Rrp47provided by FlyBase
Official Full Name
Ribosomal RNA processing 47provided by FlyBase
Primary source
FLYBASE:FBgn0030711
Locus tag
Dmel_CG8928
See related
AllianceGenome:FB:FBgn0030711
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8928; Dmel\CG8928; dRrp47; lincRNA.1007
Summary
Predicted to enable DNA binding activity and RNA binding activity. Involved in regulation of gene expression. Part of exosome (RNase complex). Orthologous to human C1D (C1D nuclear receptor corepressor). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See Rrp47 in Genome Data Viewer
Location:
14A1-14A1; 1-52 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15944897..15946249)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15838930..15840282)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Stromal interaction molecule Neighboring gene uncharacterized protein Neighboring gene mind-meld Neighboring gene mir-927 stem loop Neighboring gene long non-coding RNA:CR45527

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila melanogaster Dis3 N-terminal domains are required for ribonuclease activities, nuclear localization and exosome interactions. Mamolen M, et al. Nucleic Acids Res, 2010 Sep. PMID 20421210, Free PMC Article
  2. Genome-wide analysis reveals distinct substrate specificities of Rrp6, Dis3, and core exosome subunits. Kiss DL, et al. RNA, 2010 Apr. PMID 20185544, Free PMC Article
  3. An efficient protein complex purification method for functional proteomics in higher eukaryotes. Forler D, et al. Nat Biotechnol, 2003 Jan. PMID 12483225
  4. Interdependent nucleocytoplasmic trafficking and interactions of Dis3 with Rrp6, the core exosome and importin-alpha3. Graham AC, et al. Traffic, 2009 May. PMID 19220816, Free PMC Article
  5. Adaptation of gene loci to heterochromatin in the course of Drosophila evolution is associated with insulator proteins. Funikov SY, et al. Sci Rep, 2020 Jul 17. PMID 32681087, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in maturation of 5.8S rRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of exosome (RNase complex) IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of exosome (RNase complex) IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ribosomal RNA processing 47
Names
CG8928-PA
CG8928-PB
Rrp47-PA
Rrp47-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    15944897..15946249
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298381.1 → NP_001285310.1  ribosomal RNA processing 47, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285310.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VXL4
    Conserved Domains (1) summary
    pfam04000
    Location:32 → 105
    Sas10_Utp3; Sas10/Utp3/C1D family

  2. NM_132864.2 → NP_573092.1  ribosomal RNA processing 47, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573092.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VXL4
    Related
    FBpp0073937
    Conserved Domains (1) summary
    pfam04000
    Location:32 → 105
    Sas10_Utp3; Sas10/Utp3/C1D family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VXL4 Q9VXL4

Gene LinkOut

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