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MagR Magnetic receptor [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32513, updated on 22-Aug-2024

Summary

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Official Symbol
MagRprovided by FlyBase
Official Full Name
Magnetic receptorprovided by FlyBase
Primary source
FLYBASE:FBgn0026666
Locus tag
Dmel_CG8198
See related
AllianceGenome:FB:FBgn0026666
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:AT26381; CG8198; dMagR; Dmel\CG8198; IscA1; l(1)G0136
Summary
Predicted to enable 2 iron, 2 sulfur cluster binding activity. Involved in response to magnetism. Predicted to be active in mitochondrion. Is expressed in adult head. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 5. Orthologous to human ISCA1 (iron-sulfur cluster assembly 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See MagR in Genome Data Viewer
Location:
13E12-13E12; 1-51 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15734270..15735780)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15628303..15629813)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Actin-related protein 6 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of atomic spin-mechanical coupling in the problem of a magnetic biocompass. Cao Y, et al. Phys Rev E, 2018 Apr. PMID 29758749
  2. Computational reconstruction reveals a candidate magnetic biocompass to be likely irrelevant for magnetoreception. Friis I, et al. Sci Rep, 2017 Oct 24. PMID 29066765, Free PMC Article
  3. A magnetic protein biocompass. Qin S, et al. Nat Mater, 2016 Feb. PMID 26569474
  4. Stable intronic sequence RNAs have possible regulatory roles in Drosophila melanogaster. Pek JW, et al. J Cell Biol, 2015 Oct 26. PMID 26504165, Free PMC Article
  5. Genes for iron metabolism influence circadian rhythms in Drosophila melanogaster. Mandilaras K, et al. Metallomics, 2012 Aug. PMID 22885802

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables 2 iron, 2 sulfur cluster binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in iron-sulfur cluster assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in iron-sulfur cluster assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in protein maturation by iron-sulfur cluster transfer IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to magnetism IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
magnetic receptor
Names
CG8198-PA
CG8198-PB
IscA1 homologue
MagR-PA
MagR-PB
lethal (1) G0136
magnetoreceptor

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    15734270..15735780
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272650.1 → NP_001259579.1  magnetic receptor, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259579.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8T3X9
    Conserved Domains (1) summary
    TIGR00049
    Location:27 → 130
    TIGR00049; Iron-sulfur cluster assembly accessory protein

  2. NM_132834.2 → NP_573062.1  magnetic receptor, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573062.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    M9PJN7, Q8T3X9, Q9VXR0
    Related
    FBpp0073900
    Conserved Domains (1) summary
    TIGR00049
    Location:27 → 129
    TIGR00049; Iron-sulfur cluster assembly accessory protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8T3X9.1 Q8T3X9

Gene LinkOut

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