utp15 UTP15 small subunit processome component [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: utp15provided by ZNC
Official Full Name: UTP15 small subunit processome componentprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-3831
See related: Ensembl:ENSDARG00000002720 AllianceGenome:ZFIN:ZDB-GENE-030131-3831
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc55e07; flj12787; zgc:55320; wu:fc55e07
Summary: Acts upstream of or within positive regulation of angiogenesis. Predicted to be located in nucleus. Predicted to be active in nucleolus. Orthologous to human UTP15 (UTP15 small subunit processome component). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (7037349..7056724, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (7078208..7097762, complement)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Mutation in utp15 disrupts vascular patterning in a p53-dependent manner.
Title: Mutation in utp15 disrupts vascular patterning in a p53-dependent manner in zebrafish embryos.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within positive regulation of angiogenesis	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of transcription by RNA polymerase I	IBA Inferred from Biological aspect of Ancestor more info
involved_in rRNA processing	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within rRNA processing	IEA Inferred from Electronic Annotation more info
involved_in ribosomal small subunit biogenesis	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of small-subunit processome	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: U3 small nucleolar RNA-associated protein 15 homolog

Names: utp15, U3 small nucleolar ribonucleoprotein, homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199704.1 → NP_955998.1 U3 small nucleolar RNA-associated protein 15 homolog

See identical proteins and their annotated locations for NP_955998.1

Status: PROVISIONAL

Source sequence(s)

BC045308

UniProtKB/Swiss-Prot

Q6TGY5, Q7ZW33

Related

ENSDARP00000124648.1, ENSDART00000148774.2

Conserved Domains (4) summary

COG2319
Location:41 → 283

WD40; WD40 repeat [General function prediction only]

cd00200
Location:39 → 305

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

pfam09384
Location:343 → 487

UTP15_C; UTP15 C terminal

sd00039
Location:41 → 78

7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007129.7 Reference GRCz11 Primary Assembly

Range

7037349..7056724 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005158982.4 → XP_005159039.1 U3 small nucleolar RNA-associated protein 15 homolog isoform X1

See identical proteins and their annotated locations for XP_005159039.1

UniProtKB/Swiss-Prot

Q6TGY5, Q7ZW33

Conserved Domains (4) summary

COG2319
Location:41 → 283

WD40; WD40 repeat [General function prediction only]

cd00200
Location:39 → 305

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

pfam09384
Location:343 → 487

UTP15_C; UTP15 C terminal

sd00039
Location:41 → 78

7WD40; WD40 repeat [structural motif]