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CG8117 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32499, updated on 2-Nov-2024

Summary

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Official Symbol
CG8117provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030663
Locus tag
Dmel_CG8117
See related
AllianceGenome:FB:FBgn0030663
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
dCrsp70; Dmel\CG8117
Summary
Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human TCEA1 (transcription elongation factor A1); TCEA2 (transcription elongation factor A2); and TCEA3 (transcription elongation factor A3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG8117 in Genome Data Viewer
Location:
13E3-13E3; 1-51 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15644222..15644991)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15538255..15539024)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44423 Neighboring gene long non-coding RNA:CR44893 Neighboring gene antisense RNA:CR43299 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Conservation of enhancer location in divergent insects. Cande J, et al. Proc Natl Acad Sci U S A, 2009 Aug 25. PMID 19666595, Free PMC Article
  2. Shadow enhancers as a source of evolutionary novelty. Hong JW, et al. Science, 2008 Sep 5. PMID 18772429, Free PMC Article
  3. Systematic identification of functional orthologs based on protein network comparison. Bandyopadhyay S, et al. Genome Res, 2006 Mar. PMID 16510899, Free PMC Article
  4. A core transcriptional network for early mesoderm development in Drosophila melanogaster. Sandmann T, et al. Genes Dev, 2007 Feb 15. PMID 17322403, Free PMC Article
  5. Drosophila Med6 is required for elevated expression of a large but distinct set of developmentally regulated genes. Gim BS, et al. Mol Cell Biol, 2001 Aug. PMID 11438678, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8117-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    15644222..15644991
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132821.2 → NP_573049.2  uncharacterized protein Dmel_CG8117 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573049.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VXS6
    Related
    FBpp0073866
    Conserved Domains (2) summary
    pfam07500
    Location:3 → 109
    TFIIS_M; Transcription factor S-II (TFIIS), central domain
    cl02609
    Location:118 → 161
    Zn-ribbon; C-terminal zinc ribbon domain of RNA polymerase intrinsic transcript cleavage subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VXS6 Q9VXS6

Gene LinkOut

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