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Alg14 ALG14, UDP-N-acetylglucosaminyltransferase subunit [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32479, updated on 2-Nov-2024

Summary

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Official Symbol
Alg14provided by FlyBase
Official Full Name
ALG14, UDP-N-acetylglucosaminyltransferase subunitprovided by FlyBase
Primary source
FLYBASE:FBgn0030645
Locus tag
Dmel_CG6308
See related
AllianceGenome:FB:FBgn0030645
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
ALG14; CG6308; dAlg14; Dmel\CG6308
Summary
Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to be part of UDP-N-acetylglucosamine transferase complex. Is expressed in adult head. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 15. Orthologous to human ALG14 (ALG14 UDP-N-acetylglucosaminyltransferase subunit). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See Alg14 in Genome Data Viewer
Location:
13C4-13C4; 1-50 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15472164..15472859)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15366197..15366892)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Grip128 Neighboring gene maternal haploid Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting. Olarte MJ, et al. Dev Cell, 2020 Aug 24. PMID 32730754, Free PMC Article
  2. Diversity and functions of protein glycosylation in insects. Walski T, et al. Insect Biochem Mol Biol, 2017 Apr. PMID 28232040
  3. Protein correlation profiles identify lipid droplet proteins with high confidence. Krahmer N, et al. Mol Cell Proteomics, 2013 May. PMID 23319140, Free PMC Article
  4. Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Mummery-Widmer JL, et al. Nature, 2009 Apr 23. PMID 19363474, Free PMC Article
  5. Phenotype-based clustering of glycosylation-related genes by RNAi-mediated gene silencing. Yamamoto-Hino M, et al. Genes Cells, 2015 Jun. PMID 25940448, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting.
    Title: Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in dolichol-linked oligosaccharide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in dolichol-linked oligosaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in dolichol-linked oligosaccharide biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of UDP-N-acetylglucosamine transferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of UDP-N-acetylglucosamine transferase complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
ALG14, UDP-N-acetylglucosaminyltransferase subunit
Names
Alg14-PA
B-1,4N-acglucosaminyltransferase
CG6308-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    15472164..15472859
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132803.2 → NP_573031.1  ALG14, UDP-N-acetylglucosaminyltransferase subunit [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573031.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VXU7
    Related
    FBpp0073853
    Conserved Domains (1) summary
    pfam08660
    Location:9 → 190
    Alg14; Oligosaccharide biosynthesis protein Alg14 like
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VXU7 Q9VXU7

Gene LinkOut

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