nxf1b nuclear RNA export factor 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nxf1bprovided by ZNC
Official Full Name: nuclear RNA export factor 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-2585
See related: Ensembl:ENSDARG00000055076 AllianceGenome:ZFIN:ZDB-GENE-030131-2585
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: nxf1; im:7156527; wu:fc12d06
Summary: Predicted to enable RNA binding activity. Acts upstream of or within mRNA transport. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to several human genes including NXF1 (nuclear RNA export factor 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (26665010..26677875, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (26628245..26641205, complement)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

fb08e11.x1 (e-PCR)
- UniSTS:202757

fj88g06.x1 (e-PCR)
- UniSTS:200225

fc12d06.x1 (e-PCR)
- UniSTS:192567

fc12d06.x1 (e-PCR)
- UniSTS:192568

AI601826 (e-PCR)
- UniSTS:206181

fb61e06.x1 (e-PCR)
- UniSTS:203383

fb61e06 (e-PCR)
- UniSTS:187302

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within mRNA export from nucleus	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA transport	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within mRNA transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA transport	IGI Inferred from Genetic Interaction more info	PubMed
involved_in poly(A)+ mRNA export from nucleus	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: nuclear RNA export factor 1; nuclear RNA export factor 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007132.7 Reference GRCz11 Primary Assembly

Range

26665010..26677875 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001923926.6 → XP_001923961.1 nuclear RNA export factor 1

UniProtKB/TrEMBL

A0A8M1QLV0, F1Q7H6

Related

ENSDARP00000071848.5, ENSDART00000077381.6

Conserved Domains (6) summary

smart00804
Location:579 → 641

TAP_C; C-terminal domain of vertebrate Tap protein

sd00035
Location:246 → 288

LRR_NTF; leucine-rich repeat [structural motif]

pfam09162
Location:138 → 219

Tap-RNA_bind; Tap, RNA-binding

pfam12799
Location:287 → 333

LRR_4; Leucine Rich repeats (2 copies)

pfam13855
Location:287 → 349

LRR_8; Leucine rich repeat

cl09109
Location:413 → 561

NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...