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rad50 DNA double-strand break repair ATPase Rad50 [ Thermococcus kodakarensis KOD1 ]

Gene ID: 3235694, updated on 17-Feb-2024

Summary

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Gene symbol
rad50
Gene description
DNA double-strand break repair ATPase Rad50
Locus tag
TK_RS11110
Gene type
protein coding
Organism
Thermococcus kodakarensis KOD1 (strain: KOD1, type-material: type strain of Thermococcus kodakarensis)
Lineage
Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus
Old locus tag
TK2211
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Genomic context

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Sequence:
NC_006624.1 (1996427..1999078, complement)

NC_006624.1Genomic Context describing neighboring genes Neighboring gene ABC transporter ATP-binding protein Neighboring gene iron ABC transporter permease Neighboring gene DNA double-strand break repair nuclease NurA Neighboring gene DNA double-strand break repair protein Mre11 Neighboring gene DNA double-strand break repair helicase HerA Neighboring gene ribosomal protein S18-alanine N-acetyltransferase Neighboring gene tRNA-intron lyase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_006624.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mre11 and Rad50 from Pyrococcus furiosus: cloning and biochemical characterization reveal an evolutionarily conserved multiprotein machine. Hopfner KP, et al. J Bacteriol, 2000 Nov. PMID 11029422, Free PMC Article
  2. Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase. Hopfner KP, et al. Cell, 2001 May 18. PMID 11371344
  3. Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes. Fukui T, et al. Genome Res, 2005 Mar. PMID 15710748, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
DNA double-strand break repair ATPase Rad50

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_006624.1 Reference assembly

    Range
    1996427..1999078 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_011251161.1 DNA double-strand break repair ATPase Rad50 [Thermococcus kodakarensis]

    See identical proteins and their annotated locations for WP_011251161.1

    UniProtKB/Swiss-Prot
    Q5JHN1
    Conserved Domains (5) summary
    cd03240
    Location:788 → 876
    ABC_Rad50; ATP-binding cassette domain of Rad50
    PRK03918
    Location:1 → 882
    PRK03918; chromosome segregation protein; Provisional
    pfam04423
    Location:419 → 466
    Rad50_zn_hook; Rad50 zinc hook motif
    cl02488
    Location:449 → 549
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl21455
    Location:3 → 142
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5JHN1.1

Gene LinkOut

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