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fadD28 fatty-acid-amp ligase fadd28 (fatty-acid-amp synthetase) (fatty-acid-amp synthase) [ Mycobacterium bovis AF2122/97 ]

Gene ID: 32288260, discontinued on 3-Jun-2021
  • This record was discontinued.

Summary

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Gene symbol
fadD28
Gene description
fatty-acid-amp ligase fadd28 (fatty-acid-amp synthetase) (fatty-acid-amp synthase)
Locus tag
BQ2027_MB2966
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium bovis AF2122/97 (isolate: AF2122/97)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Location:
chromosome: Mycobacterium_bovis_AF2122/97
Sequence:
Chromosome: Mycobacterium_bovis_AF212297; NC_002945.4 (3244320..3246062)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002945.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General protein information

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Names
fatty-acid-amp ligase fadd28 (fatty-acid-amp synthetase) (fatty-acid-amp synthase)
YP_009360319.1
  • Mb2966, fadD28, len: 580 aa. Equivalent to Rv2941, len: 580 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 580 aa overlap). fadD28 (alternate gene name: acoas), fatty-acid-CoA synthetase (EC 6.2.1.-) (see citations below), almost identical to P71495 ACYL-COA SYNTHASE from Mycobacterium bovis (582 aa), FASTA scores: opt: 3828, E(): 0, (99.15% identity in 580 aa overlap); and equivalent to Q9CD79|FADD28|ML0138 ACYL-COA SYNTHETASE from Mycobacterium leprae (579 aa), FASTA scores: opt: 3183, E(): 8.8e-186, (81.9% identity in 580 aa overlap). And also highly similar to others Mycobacteria proteins e.g. O07797|FADD23|Rv3826|MTCY409.04c PUTATIVE FATTY-ACID-COA SYNTHETASE from Mycobacterium tuberculosis (584 aa); etc. Contains PS00018 EF-hand calcium-binding domain. Note that Rv2941|fadD28 and Rv2942|mmpL7 are transcriptionally coupled (proven experimentaly). Protein product from Mb2966 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2966 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing.

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002945.4 Reference assembly

    Range
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_009360319.1 fatty-acid-amp ligase fadd28 (fatty-acid-amp synthetase) (fatty-acid-amp synthase) [Mycobacterium bovis AF2122/97]

    Status: PROVISIONAL

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q02278.2

Gene LinkOut

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Molecular Biology Databases