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fabG1 3-oxoacyl-[acyl-carrier protein] reductase fabg1 (3-ketoacyl-acyl carrier protein reductase) (mycolic acid biosynthesis a protein) [ Mycobacterium bovis AF2122/97 ]

Gene ID: 32286344, discontinued on 3-Jun-2021
  • This record was discontinued.

Summary

Gene symbol
fabG1
Gene description
3-oxoacyl-[acyl-carrier protein] reductase fabg1 (3-ketoacyl-acyl carrier protein reductase) (mycolic acid biosynthesis a protein)
Locus tag
BQ2027_MB1519
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium bovis AF2122/97 (isolate: AF2122/97)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

Location:
chromosome: Mycobacterium_bovis_AF2122/97
Sequence:
Chromosome: Mycobacterium_bovis_AF212297; NC_002945.4 (1674595..1675338)

General protein information

Names
3-oxoacyl-[acyl-carrier protein] reductase fabg1 (3-ketoacyl-acyl carrier protein reductase) (mycolic acid biosynthesis a protein)
YP_009358856.1
  • Mb1519, fabG1, len: 247 aa. Equivalent to Rv1483, len: 247 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 247 aa overlap). Probable fabG1 (alternate gene name: mabA), 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100), equivalent to O07399|FABG_MYCAV 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE from Mycobacterium avium (255 aa); P71534|FABG_MYCSM 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE from Mycobacterium smegmatis (255 aa); and NP_302228.1|NC_002677 3-oxoacyl-[ACP] reductase (aka MabA) from Mycobacterium leprae (253 aa). Also highly similar to many e.g. T36779 probable 3-oxacyl-(acyl-carrier-protein) reductase from Streptomyces coelicolor (234 aa); FABG_ECOLI|P25716|NP_415611.1|NC_000913 3-oxoacyl-[acyl-carrier-protein] reductase from Escherichia coli strain K12 (244 aa), FASTA scores: opt: 664, E(): 6.8e-35, (44.4% identity in 241 aa overlap); etc. Contains PS00061 Short-chain dehydrogenases/reductases family signature. BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES (SDR) FAMILY. Protein product from Mb1519 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1519 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002945.4 Reference assembly

    Range
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_009358856.1 3-oxoacyl-[acyl-carrier protein] reductase fabg1 (3-ketoacyl-acyl carrier protein reductase) (mycolic acid biosynthesis a protein) [Mycobacterium bovis AF2122/97]

    Status: PROVISIONAL