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CG2247 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32111, updated on 2-Nov-2024

Summary

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Official Symbol
CG2247provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030320
Locus tag
Dmel_CG2247
See related
AllianceGenome:FB:FBgn0030320
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG2247; FBXL5
Summary
Involved in defense response to bacterium. Located in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG2247 in Genome Data Viewer
Location:
10C10-10D1; 1-35 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11606290..11611652, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11500323..11505685, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene rhomboid-4 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Replication protein A3 Neighboring gene Methoprene-tolerant

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. How Many Parameters Does It Take to Describe Disease Tolerance? Louie A, et al. PLoS Biol, 2016 Apr. PMID 27088212, Free PMC Article
  2. Cis-regulatory variation is typically polyallelic in Drosophila. Gruber JD, et al. Genetics, 2009 Feb. PMID 19064705, Free PMC Article
  3. Identification of Drosophila mutants altering defense of and endurance to Listeria monocytogenes infection. Ayres JS, et al. Genetics, 2008 Mar. PMID 18245331, Free PMC Article
  4. The Integrator complex cleaves nascent mRNAs to attenuate transcription. Tatomer DC, et al. Genes Dev, 2019 Nov 1. PMID 31530651, Free PMC Article
  5. SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56. Barbosa P, et al. J Cell Biol, 2021 Feb 1. PMID 33382409, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISM
Inferred from Sequence Model
more info
  
involved_in defense response to bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex ISM
Inferred from Sequence Model
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG2247-PA
CG2247-PB
CG2247-PC
CG2247-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    11606290..11611652 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132507.2 → NP_572735.1  uncharacterized protein Dmel_CG2247, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572735.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VYW5
    Related
    FBpp0073381
    Conserved Domains (1) summary
    pfam12937
    Location:647 → 686
    F-box-like; F-box-like

  2. NM_001258697.2 → NP_001245626.1  uncharacterized protein Dmel_CG2247, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245626.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NED4
    Conserved Domains (1) summary
    pfam12937
    Location:543 → 582
    F-box-like; F-box-like

  3. NM_001258698.2 → NP_001245627.1  uncharacterized protein Dmel_CG2247, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245627.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NF18
    Conserved Domains (1) summary
    pfam12937
    Location:646 → 685
    F-box-like; F-box-like

  4. NM_001258696.2 → NP_001245625.1  uncharacterized protein Dmel_CG2247, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245625.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VYW5
    Conserved Domains (1) summary
    pfam12937
    Location:647 → 686
    F-box-like; F-box-like
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9NED4 M9NED4
M9NF18 M9NF18
Q9VYW5 Q9VYW5

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