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Map7d3 MAP7 domain containing 3 [ Mus musculus (house mouse) ]

Gene ID: 320923, updated on 17-Aug-2024

Summary

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Official Symbol
Map7d3provided by MGI
Official Full Name
MAP7 domain containing 3provided by MGI
Primary source
MGI:MGI:2445051
See related
Ensembl:ENSMUSG00000067878 AllianceGenome:MGI:2445051
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mtap7d3; 4933424A10Rik
Summary
Predicted to enable microtubule binding activity. Predicted to be involved in microtubule polymerization. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in microtubule cytoskeleton. Orthologous to human MAP7D3 (MAP7 domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
human all
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Genomic context

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Location:
X A6; X 30.16 cM
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (55840193..55867866, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (56794833..56822490, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 26312 Neighboring gene four and a half LIM domains 1 Neighboring gene predicted gene, 23258 Neighboring gene STARR-seq mESC enhancer starr_47209 Neighboring gene STARR-seq mESC enhancer starr_47210 Neighboring gene adhesion G protein-coupled receptor G4 Neighboring gene bombesin-like receptor 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Human X chromosome exome sequencing identifies BCORL1 as contributor to spermatogenesis. Lu C, et al. J Med Genet, 2021 Jan. PMID 32376790
  2. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Human X chromosome exome sequencing identifies BCORL1 as contributor to spermatogenesis.
    Title: Human X chromosome exome sequencing identifies BCORL1 as contributor to spermatogenesis.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables microtubule binding ISO
Inferred from Sequence Orthology
more info
  
enables tubulin binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
  
involved_in microtubule polymerization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
is_active_in microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
MAP7 domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177293.3 → NP_796267.2  MAP7 domain-containing protein 3

    See identical proteins and their annotated locations for NP_796267.2

    Status: VALIDATED

    Source sequence(s)
    AK030211, AK048385, BB610806, BC096764
    Consensus CDS
    CCDS40982.1
    UniProtKB/Swiss-Prot
    A2AEY4, Q0VF65, Q8C7V9, Q8C857, Q8CDD4
    Related
    ENSMUSP00000110414.2, ENSMUST00000114766.8
    Conserved Domains (2) summary
    pfam05672
    Location:558 → 657
    MAP7; MAP7 (E-MAP-115) family
    pfam11208
    Location:62 → 129
    DUF2992; Protein of unknown function (DUF2992)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    55840193..55867866 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006528089.3 → XP_006528152.1  MAP7 domain-containing protein 3 isoform X2

    Conserved Domains (3) summary
    PRK09510
    Location:114 → 193
    tolA; cell envelope integrity inner membrane protein TolA; Provisional
    pfam05672
    Location:614 → 711
    MAP7; MAP7 (E-MAP-115) family
    pfam16598
    Location:44 → 114
    Edc3_linker; Linker region of enhancer of mRNA-decapping protein 3

  2. XM_036161989.1 → XP_036017882.1  MAP7 domain-containing protein 3 isoform X3

    Conserved Domains (2) summary
    PRK09510
    Location:114 → 193
    tolA; cell envelope integrity inner membrane protein TolA; Provisional
    NF033875
    Location:530 → 795
    Agg_substance; LPXTG-anchored aggregation substance

  3. XM_006528088.3 → XP_006528151.1  MAP7 domain-containing protein 3 isoform X1

    Conserved Domains (3) summary
    PRK09510
    Location:114 → 193
    tolA; cell envelope integrity inner membrane protein TolA; Provisional
    pfam05672
    Location:614 → 711
    MAP7; MAP7 (E-MAP-115) family
    pfam16598
    Location:44 → 114
    Edc3_linker; Linker region of enhancer of mRNA-decapping protein 3

RNA

  1. XR_878106.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2AEY4.1 GenPept UniProtKB/Swiss-Prot:A2AEY4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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