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v - vermilion

Enables heme binding activity and tryptophan 2,3-dioxygenase activity. Involved in several processes, including ommochrome biosynthetic process; protein homotetramerization; and tryptophan catabolic process to kynurenine. Is expressed in embryonic head epidermis and embryonic/larval fat body. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Orthologous to human TDO2 (tryptophan 2,3-dioxygenase). [provided by Alliance of Genome Resources, Apr 2022]

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Species Gene Architecture aa