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Prr18 proline rich 18 [ Mus musculus (house mouse) ]

Gene ID: 320111, updated on 2-Nov-2024

Summary

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Official Symbol
Prr18provided by MGI
Official Full Name
proline rich 18provided by MGI
Primary source
MGI:MGI:2443403
See related
Ensembl:ENSMUSG00000055945 AllianceGenome:MGI:2443403
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9630019K15Rik
Summary
Is expressed in trachea epithelium. Orthologous to human PRR18 (proline rich 18). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in cerebellum adult (RPKM 16.8), cortex adult (RPKM 8.8) and 6 other tissues See more
Orthologs
human all
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Genomic context

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See Prr18 in Genome Data Viewer
Location:
17 A1; 17 4.92 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (8546378..8562945)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (8340406..8344113)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1188 Neighboring gene RIKEN cDNA 4930506C21 gene Neighboring gene mitochondrial pyruvate carrier 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:8503785-8503968 Neighboring gene SFT2 domain containing 1 Neighboring gene predicted gene, 46592 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:8564858-8564967 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:8565311-8565494 Neighboring gene STARR-positive B cell enhancer ABC_E4191 Neighboring gene protein FAM32A pseudogene Neighboring gene brachyury 2 Neighboring gene predicted gene, 16702 Neighboring gene ribosomal protein L15 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Chloride channels regulate differentiation and barrier functions of the mammalian airway. He M, et al. Elife, 2020 Apr 14. PMID 32286221, Free PMC Article
  2. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
proline-rich protein 18
Names
proline rich region 18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399587.1 → NP_001386516.1  proline-rich protein 18 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC164431
    UniProtKB/Swiss-Prot
    Q6PAN7, Q8BR84, Q8CA32, Q8CBI5
    Related
    ENSMUSP00000069019.7, ENSMUST00000069742.8

  2. NM_178774.4 → NP_848889.3  proline-rich protein 18 isoform 1

    See identical proteins and their annotated locations for NP_848889.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript but encodes the functional protein.
    Source sequence(s)
    AC164431, AK045379, BC060190
    Consensus CDS
    CCDS28382.1
    UniProtKB/Swiss-Prot
    Q6PAN7, Q8BR84, Q8CA32, Q8CBI5
    Related
    ENSMUSP00000127393.2, ENSMUST00000163887.2
    Conserved Domains (1) summary
    pfam15671
    Location:55 → 307
    PRR18; Proline-rich protein family 18

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    8546378..8562945
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036160645.1 → XP_036016538.1  proline-rich protein 18 isoform X1

    UniProtKB/Swiss-Prot
    Q6PAN7, Q8BR84, Q8CA32, Q8CBI5
    Conserved Domains (1) summary
    pfam15671
    Location:55 → 307
    PRR18; Proline-rich protein family 18

  2. XM_036160644.1 → XP_036016537.1  proline-rich protein 18 isoform X1

    UniProtKB/Swiss-Prot
    Q6PAN7, Q8BR84, Q8CA32, Q8CBI5
    Conserved Domains (1) summary
    pfam15671
    Location:55 → 307
    PRR18; Proline-rich protein family 18
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6PAN7.2 GenPept UniProtKB/Swiss-Prot:Q6PAN7

Gene LinkOut

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