Zbtb39 zinc finger and BTB domain containing 39 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zbtb39provided by MGI
Official Full Name: zinc finger and BTB domain containing 39provided by MGI
Primary source: MGI:MGI:2443316
See related: Ensembl:ENSMUSG00000044617 AllianceGenome:MGI:2443316
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: mKIAA0352; 7030401O21Rik
Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Predicted to be active in nucleoplasm. Orthologous to human ZBTB39 (zinc finger and BTB domain containing 39). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 6.7), ovary adult (RPKM 5.2) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 10 D3; 10 74.98 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (127575399..127583218)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (127739530..127747349)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of cytokine production	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of immune system process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: zinc finger and BTB domain-containing protein 39

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_198035.2 → NP_932152.1 zinc finger and BTB domain-containing protein 39

See identical proteins and their annotated locations for NP_932152.1

Status: VALIDATED

Source sequence(s)

AC129576, AC160970

Consensus CDS

CCDS24249.1

UniProtKB/TrEMBL

Q6A082, Q6PDK0

Related

ENSMUSP00000052717.8, ENSMUST00000054287.9

Conserved Domains (4) summary

smart00225
Location:31 → 120

BTB; Broad-Complex, Tramtrack and Bric a brac

sd00017
Location:607 → 627

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00651
Location:20 → 119

BTB; BTB/POZ domain

pfam13465
Location:619 → 642

zf-H2C2_2; Zinc-finger double domain